Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review

Thymomas are tumours frequently associated with autoimmune manifestations or immunodeficiencies like Good syndrome. In rare cases, pure white cells aplasia (PWCA) has been described in association with thymomas. PWCA is characterized by agranulocytosis of autoimmune background primary refractory to...

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Autores principales: Céspedes López, Roberto, Amutio Díez, Elena, Martín Martitegui, Xabier, Balerdi Malcorra, Amaia, Insunza Oleaga, Lucia, Arzuaga‐Méndez, Javier, Moreno Gámiz, Maite, Saiz Camín, Mónica, Aberasturi Plata, Yoseba, García‐Ruíz, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083807/
https://www.ncbi.nlm.nih.gov/pubmed/35582161
http://dx.doi.org/10.1002/ccr3.5742
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author Céspedes López, Roberto
Amutio Díez, Elena
Martín Martitegui, Xabier
Balerdi Malcorra, Amaia
Insunza Oleaga, Lucia
Arzuaga‐Méndez, Javier
Moreno Gámiz, Maite
Saiz Camín, Mónica
Aberasturi Plata, Yoseba
García‐Ruíz, Juan Carlos
author_facet Céspedes López, Roberto
Amutio Díez, Elena
Martín Martitegui, Xabier
Balerdi Malcorra, Amaia
Insunza Oleaga, Lucia
Arzuaga‐Méndez, Javier
Moreno Gámiz, Maite
Saiz Camín, Mónica
Aberasturi Plata, Yoseba
García‐Ruíz, Juan Carlos
author_sort Céspedes López, Roberto
collection PubMed
description Thymomas are tumours frequently associated with autoimmune manifestations or immunodeficiencies like Good syndrome. In rare cases, pure white cells aplasia (PWCA) has been described in association with thymomas. PWCA is characterized by agranulocytosis of autoimmune background primary refractory to granulocyte colony‐stimulating factor (G‐CSF). It is necessary the use of immunosuppressor to allow granulocyte recovery. Without treatment, it could be fatal.
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spelling pubmed-90838072022-05-16 Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review Céspedes López, Roberto Amutio Díez, Elena Martín Martitegui, Xabier Balerdi Malcorra, Amaia Insunza Oleaga, Lucia Arzuaga‐Méndez, Javier Moreno Gámiz, Maite Saiz Camín, Mónica Aberasturi Plata, Yoseba García‐Ruíz, Juan Carlos Clin Case Rep Case Reports Thymomas are tumours frequently associated with autoimmune manifestations or immunodeficiencies like Good syndrome. In rare cases, pure white cells aplasia (PWCA) has been described in association with thymomas. PWCA is characterized by agranulocytosis of autoimmune background primary refractory to granulocyte colony‐stimulating factor (G‐CSF). It is necessary the use of immunosuppressor to allow granulocyte recovery. Without treatment, it could be fatal. John Wiley and Sons Inc. 2022-05-09 /pmc/articles/PMC9083807/ /pubmed/35582161 http://dx.doi.org/10.1002/ccr3.5742 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Céspedes López, Roberto
Amutio Díez, Elena
Martín Martitegui, Xabier
Balerdi Malcorra, Amaia
Insunza Oleaga, Lucia
Arzuaga‐Méndez, Javier
Moreno Gámiz, Maite
Saiz Camín, Mónica
Aberasturi Plata, Yoseba
García‐Ruíz, Juan Carlos
Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review
title Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review
title_full Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review
title_fullStr Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review
title_full_unstemmed Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review
title_short Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review
title_sort pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: responses to immunosuppression and literature review
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083807/
https://www.ncbi.nlm.nih.gov/pubmed/35582161
http://dx.doi.org/10.1002/ccr3.5742
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