N(2)-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis

A new method was developed to synthesize N(2)-alkyl-substituted 1,2,3-triazoles via gold catalyzed alkylation of vinyl ethers with mono- and unsubstituted NH-1,2,3-triazoles and benzotriazole. A hydrogen bond between the oxygen atom of the vinyl ethers, activated via the gold catalyst, and the NH-1,...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Guoli, Sun, Chenyang, Li, Yan, Li, Xiaoxiao, Zhao, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083898/
https://www.ncbi.nlm.nih.gov/pubmed/35542727
http://dx.doi.org/10.1039/c8ra04790a
_version_ 1784703500813336576
author Luo, Guoli
Sun, Chenyang
Li, Yan
Li, Xiaoxiao
Zhao, Zhigang
author_facet Luo, Guoli
Sun, Chenyang
Li, Yan
Li, Xiaoxiao
Zhao, Zhigang
author_sort Luo, Guoli
collection PubMed
description A new method was developed to synthesize N(2)-alkyl-substituted 1,2,3-triazoles via gold catalyzed alkylation of vinyl ethers with mono- and unsubstituted NH-1,2,3-triazoles and benzotriazole. A hydrogen bond between the oxygen atom of the vinyl ethers, activated via the gold catalyst, and the NH-1,2,3-triazoles was supposed to be generated, which selectively gave the N(2)-alkylation products.
format Online
Article
Text
id pubmed-9083898
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90838982022-05-09 N(2)-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis Luo, Guoli Sun, Chenyang Li, Yan Li, Xiaoxiao Zhao, Zhigang RSC Adv Chemistry A new method was developed to synthesize N(2)-alkyl-substituted 1,2,3-triazoles via gold catalyzed alkylation of vinyl ethers with mono- and unsubstituted NH-1,2,3-triazoles and benzotriazole. A hydrogen bond between the oxygen atom of the vinyl ethers, activated via the gold catalyst, and the NH-1,2,3-triazoles was supposed to be generated, which selectively gave the N(2)-alkylation products. The Royal Society of Chemistry 2018-08-02 /pmc/articles/PMC9083898/ /pubmed/35542727 http://dx.doi.org/10.1039/c8ra04790a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Luo, Guoli
Sun, Chenyang
Li, Yan
Li, Xiaoxiao
Zhao, Zhigang
N(2)-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis
title N(2)-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis
title_full N(2)-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis
title_fullStr N(2)-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis
title_full_unstemmed N(2)-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis
title_short N(2)-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis
title_sort n(2)-selective alkylation of nh-1,2,3-triazoles with vinyl ethers via gold catalysis
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083898/
https://www.ncbi.nlm.nih.gov/pubmed/35542727
http://dx.doi.org/10.1039/c8ra04790a
work_keys_str_mv AT luoguoli n2selectivealkylationofnh123triazoleswithvinylethersviagoldcatalysis
AT sunchenyang n2selectivealkylationofnh123triazoleswithvinylethersviagoldcatalysis
AT liyan n2selectivealkylationofnh123triazoleswithvinylethersviagoldcatalysis
AT lixiaoxiao n2selectivealkylationofnh123triazoleswithvinylethersviagoldcatalysis
AT zhaozhigang n2selectivealkylationofnh123triazoleswithvinylethersviagoldcatalysis

Ejemplares similares