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Expedient synthesis of eumelanin-inspired 5,6-dihydroxyindole-2-carboxylate ethyl ester derivatives

Dihydroxyindoles such as 5,6-dihydroxyindole-2-carboxylic acid (DHICA) are the main monomer units of eumelanin, the black to brown pigment in humans, and have emerging biological roles beyond melanin. Elaboration of commercially available 5,6-dimethoxy-2-carboxylate ethyl ester provides ready access...

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Detalles Bibliográficos
Autores principales: Aebly, Andrew H., Levy, Jeffrey N., Steger, Benjamin J., Quirke, Jonathan C., Belitsky, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083952/
https://www.ncbi.nlm.nih.gov/pubmed/35542496
http://dx.doi.org/10.1039/c8ra06148c