Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness

The dynamics of SARS-CoV-2 replication and shedding in humans remain poorly understood. We captured the dynamics of infectious virus and viral RNA shedding during acute infection through daily longitudinal sampling of 60 individuals for up to 14 days. By fitting mechanistic models, we directly estim...

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Detalles Bibliográficos
Autores principales: Ke, Ruian, Martinez, Pamela P., Smith, Rebecca L., Gibson, Laura L., Mirza, Agha, Conte, Madison, Gallagher, Nicholas, Luo, Chun Huai, Jarrett, Junko, Zhou, Ruifeng, Conte, Abigail, Liu, Tongyu, Farjo, Mireille, Walden, Kimberly K.O., Rendon, Gloria, Fields, Christopher J., Wang, Leyi, Fredrickson, Richard, Edmonson, Darci C., Baughman, Melinda E., Chiu, Karen K., Choi, Hannah, Scardina, Kevin R., Bradley, Shannon, Gloss, Stacy L., Reinhart, Crystal, Yedetore, Jagadeesh, Quicksall, Jessica, Owens, Alyssa N., Broach, John, Barton, Bruce, Lazar, Peter, Heetderks, William J., Robinson, Matthew L., Mostafa, Heba H., Manabe, Yukari C., Pekosz, Andrew, McManus, David D., Brooke, Christopher B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084242/
https://www.ncbi.nlm.nih.gov/pubmed/35484231
http://dx.doi.org/10.1038/s41564-022-01105-z

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