Halting ErbB-2 isoforms retrograde transport to the nucleus as a new theragnostic approach for triple-negative breast cancer

Triple-negative breast cancer (TNBC) is clinically defined by the absence of estrogen and progesterone receptors and the lack of membrane overexpression or gene amplification of receptor tyrosine kinase ErbB-2/HER2. Due to TNBC heterogeneity, clinical biomarkers and targeted therapies for this disea...

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Detalles Bibliográficos
Autores principales: Madera, Santiago, Izzo, Franco, Chervo, María F., Dupont, Agustina, Chiauzzi, Violeta A., Bruni, Sofia, Petrillo, Ezequiel, Merin, Sharon S., De Martino, Mara, Montero, Diego, Levit, Claudio, Lebersztein, Gabriel, Anfuso, Fabiana, Roldán Deamicis, Agustina, Mercogliano, María F., Proietti, Cecilia J., Schillaci, Roxana, Elizalde, Patricia V., Cordo Russo, Rosalía I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084267/
https://www.ncbi.nlm.nih.gov/pubmed/35534460
http://dx.doi.org/10.1038/s41419-022-04855-0

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