Current advances of carbene-mediated photoaffinity labeling in medicinal chemistry

Photoaffinity labeling (PAL) in combination with a chemical probe to covalently bind its target upon UV irradiation has demonstrated considerable promise in drug discovery for identifying new drug targets and binding sites. In particular, carbene-mediated photoaffinity labeling (cmPAL) has been wide...

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Detalles Bibliográficos
Autores principales: Ge, Sha-Sha, Chen, Biao, Wu, Yuan-Yuan, Long, Qing-Su, Zhao, Yong-Liang, Wang, Pei-Yi, Yang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084484/
https://www.ncbi.nlm.nih.gov/pubmed/35547988
http://dx.doi.org/10.1039/c8ra03538e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084484/
https://www.ncbi.nlm.nih.gov/pubmed/35547988
http://dx.doi.org/10.1039/c8ra03538e

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