MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

MDGA molecules can bind neuroligins and interfere with trans-synaptic interactions to neurexins, thereby impairing synapse development. However, the subcellular localization and dynamics of MDGAs, or their specific action mode in neurons remain unclear. Here, surface immunostaining of endogenous MDG...

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Detalles Bibliográficos
Autores principales: Toledo, Andrea, Letellier, Mathieu, Bimbi, Giorgia, Tessier, Béatrice, Daburon, Sophie, Favereaux, Alexandre, Chamma, Ingrid, Vennekens, Kristel, Vanderlinden, Jeroen, Sainlos, Matthieu, de Wit, Joris, Choquet, Daniel, Thoumine, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084894/
https://www.ncbi.nlm.nih.gov/pubmed/35532105
http://dx.doi.org/10.7554/eLife.75233

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