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Low-Molecular Weight Protamine Overcomes Chondroitin Sulfate Inhibition of Neural Regeneration

Protamine is an arginine-rich peptide that replaces histones in the DNA-protein complex during spermatogenesis. Protamine is clinically used in cardiopulmonary bypass surgery to neutralize the effects of heparin that is required during the treatment. Here we demonstrate that protamine and its 14–22...

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Detalles Bibliográficos
Autores principales: Kulesskaya, Natalia, Mugantseva, Ekaterina, Minkeviciene, Rimante, Acosta, Natalia, Rouhiainen, Ari, Kuja-Panula, Juha, Kislin, Mikhail, Piirainen, Sami, Paveliev, Mikhail, Rauvala, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084902/
https://www.ncbi.nlm.nih.gov/pubmed/35547817
http://dx.doi.org/10.3389/fcell.2022.865275

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