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METNET: a phase II trial of metformin in patients with well-differentiated neuroendocrine tumours

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BACKGROUND: Preclinical studies have suggested that metformin has anti-tumour effects, likely due to blockage of mammalian target of rapamycin pathway through adenosine monophosphate-activated protein kinase and decreased insulin levels. A retrospective study showed that metformin added to everolimu...

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Detalles Bibliográficos
Autores principales:	Glasberg, João, Talans, Aley, Giollo, Thomás Rivelli, Recchimuzzi, Débora Zachello, Neto, João Evangelista Bezerra, Lopez, Rossana Veronica Mendonza, Hoff, Paulo Marcelo Gehm, Riechelmann, Rachel P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cancer Intelligence 2022
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085158/ https://www.ncbi.nlm.nih.gov/pubmed/35685961 http://dx.doi.org/10.3332/ecancer.2022.1369

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