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Radiographic and clinical outcome of tibial plateau fractures treated with bone allograft

BACKGROUND: To determine the clinical outcome of patients who had been treated with bone allografts during open reduction and internal fixation (ORIF) of tibial head fractures. METHODS: Patients who suffered a medial, lateral, or bicondylar fracture of the tibial plateau and underwent surgical treat...

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Autores principales: Meiser, Sarah, Arora, Rohit, Petersen, Johannes, Keiler, Alexander, Liebensteiner, Michael C., Pallua, Johannes Dominikus, Wurm, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085366/
https://www.ncbi.nlm.nih.gov/pubmed/35534713
http://dx.doi.org/10.1007/s00402-022-04461-x
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author Meiser, Sarah
Arora, Rohit
Petersen, Johannes
Keiler, Alexander
Liebensteiner, Michael C.
Pallua, Johannes Dominikus
Wurm, Alexander
author_facet Meiser, Sarah
Arora, Rohit
Petersen, Johannes
Keiler, Alexander
Liebensteiner, Michael C.
Pallua, Johannes Dominikus
Wurm, Alexander
author_sort Meiser, Sarah
collection PubMed
description BACKGROUND: To determine the clinical outcome of patients who had been treated with bone allografts during open reduction and internal fixation (ORIF) of tibial head fractures. METHODS: Patients who suffered a medial, lateral, or bicondylar fracture of the tibial plateau and underwent surgical treatment by open reduction and internal fixation (ORIF) using human femoral head bone allografts were included. Patients were invited to provide information for the following: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), EuroQol Five Dimension score (EQ-5D), Lower Extremity Functional Scale (LEFS) and Parker Mobility Score. Bone mineral density (BMD) of the allograft area and the healthy human bone tissue were measured by quantitative computed tomography. RESULTS: A total of 22 patients with a mean follow-up time of 2.88 ± 2.46 years were included in our study. The most common fractures observed in this study were classified as Schatzker II (11 patients, 50.0%) or AO/OTA 41.B3 (12 patients, 54.5%) fractures. Postoperative WOMAC total was 13.0 (IQR = 16.3, range 0–33). Median quality of life (EQ-5D) score was 0.887 ± 0.121 (range 0.361–1.000). Median Lower Extremity Functional Scale (LEFS) score was 57.5 ± 19.0 (range 33–79). Mean Parker Mobility Score was 9 (range 6–9). Median bone mineral density (BMD) for the whole group was 300.04 ± 226.02 mg/cm(3) (range − 88.68 to 555.06 mg/cm(3)) for region of interest (ROI 5) (central), 214.80 ± 167.45 mg/cm(3) (range − 7.16 to 597.21 mg/cm(3)) for ROI 1–4 (marginal zones: medial, lateral, ventral, dorsal) and 168.14 ± 65.54 mg/cm(3) (range 17.47–208.97 mg/cm(3)) for healthy bone tissue (femur and tibia). CONCLUSION: Based on WOMAC scores, LEFS, ambulatory status, and quality of life findings, it can be concluded that following tibial head ORIF with allograft bone patients has promising results.
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spelling pubmed-90853662022-05-10 Radiographic and clinical outcome of tibial plateau fractures treated with bone allograft Meiser, Sarah Arora, Rohit Petersen, Johannes Keiler, Alexander Liebensteiner, Michael C. Pallua, Johannes Dominikus Wurm, Alexander Arch Orthop Trauma Surg Trauma Surgery BACKGROUND: To determine the clinical outcome of patients who had been treated with bone allografts during open reduction and internal fixation (ORIF) of tibial head fractures. METHODS: Patients who suffered a medial, lateral, or bicondylar fracture of the tibial plateau and underwent surgical treatment by open reduction and internal fixation (ORIF) using human femoral head bone allografts were included. Patients were invited to provide information for the following: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), EuroQol Five Dimension score (EQ-5D), Lower Extremity Functional Scale (LEFS) and Parker Mobility Score. Bone mineral density (BMD) of the allograft area and the healthy human bone tissue were measured by quantitative computed tomography. RESULTS: A total of 22 patients with a mean follow-up time of 2.88 ± 2.46 years were included in our study. The most common fractures observed in this study were classified as Schatzker II (11 patients, 50.0%) or AO/OTA 41.B3 (12 patients, 54.5%) fractures. Postoperative WOMAC total was 13.0 (IQR = 16.3, range 0–33). Median quality of life (EQ-5D) score was 0.887 ± 0.121 (range 0.361–1.000). Median Lower Extremity Functional Scale (LEFS) score was 57.5 ± 19.0 (range 33–79). Mean Parker Mobility Score was 9 (range 6–9). Median bone mineral density (BMD) for the whole group was 300.04 ± 226.02 mg/cm(3) (range − 88.68 to 555.06 mg/cm(3)) for region of interest (ROI 5) (central), 214.80 ± 167.45 mg/cm(3) (range − 7.16 to 597.21 mg/cm(3)) for ROI 1–4 (marginal zones: medial, lateral, ventral, dorsal) and 168.14 ± 65.54 mg/cm(3) (range 17.47–208.97 mg/cm(3)) for healthy bone tissue (femur and tibia). CONCLUSION: Based on WOMAC scores, LEFS, ambulatory status, and quality of life findings, it can be concluded that following tibial head ORIF with allograft bone patients has promising results. Springer Berlin Heidelberg 2022-05-10 2023 /pmc/articles/PMC9085366/ /pubmed/35534713 http://dx.doi.org/10.1007/s00402-022-04461-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Trauma Surgery
Meiser, Sarah
Arora, Rohit
Petersen, Johannes
Keiler, Alexander
Liebensteiner, Michael C.
Pallua, Johannes Dominikus
Wurm, Alexander
Radiographic and clinical outcome of tibial plateau fractures treated with bone allograft
title Radiographic and clinical outcome of tibial plateau fractures treated with bone allograft
title_full Radiographic and clinical outcome of tibial plateau fractures treated with bone allograft
title_fullStr Radiographic and clinical outcome of tibial plateau fractures treated with bone allograft
title_full_unstemmed Radiographic and clinical outcome of tibial plateau fractures treated with bone allograft
title_short Radiographic and clinical outcome of tibial plateau fractures treated with bone allograft
title_sort radiographic and clinical outcome of tibial plateau fractures treated with bone allograft
topic Trauma Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085366/
https://www.ncbi.nlm.nih.gov/pubmed/35534713
http://dx.doi.org/10.1007/s00402-022-04461-x
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