Silver-catalyzed direct benzylation of acetanilide: a highly efficient approach to unsymmetrical triarylmethanes

A highly efficient silver-catalyzed dibenzylation of acetanilides by employing the benzhydrol derivatives as the coupling partners to yield triphenylmethane derivatives has been developed. Various functional groups were tolerated, leading to the corresponding products in moderate to good yields. Pre...

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Detalles Bibliográficos
Autores principales: Li, Yuting, Zhu, Yan, Tu, Guangliang, Zhang, Jingyu, Zhao, Yingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085427/
https://www.ncbi.nlm.nih.gov/pubmed/35546817
http://dx.doi.org/10.1039/c8ra06780e
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author Li, Yuting
Zhu, Yan
Tu, Guangliang
Zhang, Jingyu
Zhao, Yingsheng
author_facet Li, Yuting
Zhu, Yan
Tu, Guangliang
Zhang, Jingyu
Zhao, Yingsheng
author_sort Li, Yuting
collection PubMed
description A highly efficient silver-catalyzed dibenzylation of acetanilides by employing the benzhydrol derivatives as the coupling partners to yield triphenylmethane derivatives has been developed. Various functional groups were tolerated, leading to the corresponding products in moderate to good yields. Preliminary experimental results indicated that the silver ions activate the arene rings and the strong acid TfOH provides the carbocations.
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spelling pubmed-90854272022-05-10 Silver-catalyzed direct benzylation of acetanilide: a highly efficient approach to unsymmetrical triarylmethanes Li, Yuting Zhu, Yan Tu, Guangliang Zhang, Jingyu Zhao, Yingsheng RSC Adv Chemistry A highly efficient silver-catalyzed dibenzylation of acetanilides by employing the benzhydrol derivatives as the coupling partners to yield triphenylmethane derivatives has been developed. Various functional groups were tolerated, leading to the corresponding products in moderate to good yields. Preliminary experimental results indicated that the silver ions activate the arene rings and the strong acid TfOH provides the carbocations. The Royal Society of Chemistry 2018-08-28 /pmc/articles/PMC9085427/ /pubmed/35546817 http://dx.doi.org/10.1039/c8ra06780e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Li, Yuting
Zhu, Yan
Tu, Guangliang
Zhang, Jingyu
Zhao, Yingsheng
Silver-catalyzed direct benzylation of acetanilide: a highly efficient approach to unsymmetrical triarylmethanes
title Silver-catalyzed direct benzylation of acetanilide: a highly efficient approach to unsymmetrical triarylmethanes
title_full Silver-catalyzed direct benzylation of acetanilide: a highly efficient approach to unsymmetrical triarylmethanes
title_fullStr Silver-catalyzed direct benzylation of acetanilide: a highly efficient approach to unsymmetrical triarylmethanes
title_full_unstemmed Silver-catalyzed direct benzylation of acetanilide: a highly efficient approach to unsymmetrical triarylmethanes
title_short Silver-catalyzed direct benzylation of acetanilide: a highly efficient approach to unsymmetrical triarylmethanes
title_sort silver-catalyzed direct benzylation of acetanilide: a highly efficient approach to unsymmetrical triarylmethanes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085427/
https://www.ncbi.nlm.nih.gov/pubmed/35546817
http://dx.doi.org/10.1039/c8ra06780e
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AT tuguangliang silvercatalyzeddirectbenzylationofacetanilideahighlyefficientapproachtounsymmetricaltriarylmethanes
AT zhangjingyu silvercatalyzeddirectbenzylationofacetanilideahighlyefficientapproachtounsymmetricaltriarylmethanes
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