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Exposure and respiratory infection risk via the short-range airborne route

Leading health authorities have suggested short-range airborne transmission as a major route of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, there is no simple method to assess the short-range airborne infection risk or identify its governing parameters. We proposed a short...

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Detalles Bibliográficos
Autores principales: Jia, Wei, Wei, Jianjian, Cheng, Pan, Wang, Qun, Li, Yuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085449/
https://www.ncbi.nlm.nih.gov/pubmed/35574565
http://dx.doi.org/10.1016/j.buildenv.2022.109166
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author Jia, Wei
Wei, Jianjian
Cheng, Pan
Wang, Qun
Li, Yuguo
author_facet Jia, Wei
Wei, Jianjian
Cheng, Pan
Wang, Qun
Li, Yuguo
author_sort Jia, Wei
collection PubMed
description Leading health authorities have suggested short-range airborne transmission as a major route of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, there is no simple method to assess the short-range airborne infection risk or identify its governing parameters. We proposed a short-range airborne infection risk assessment model based on the continuum model and two-stage jet model. The effects of ventilation, physical distance and activity intensity on the short-range airborne exposure were studied systematically. The results suggested that increasing physical distance and ventilation reduced short-range airborne exposure and infection risk. However, a diminishing return phenomenon was observed when the ventilation rate or physical distance was beyond a certain threshold. When the infectious quantum concentration was less than 1 quantum/L at the mouth, our newly defined threshold distance and threshold ventilation rate were independent of quantum concentration. We estimated threshold distances of 0.59, 1.1, 1.7 and 2.6 m for sedentary/passive, light, moderate and intense activities, respectively. At these distances, the threshold ventilation was estimated to be 8, 20, 43, and 83 L/s per person, respectively. The findings show that both physical distancing and adequate ventilation are essential for minimising infection risk, especially in high-intensity activity or densely populated spaces.
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spelling pubmed-90854492022-05-10 Exposure and respiratory infection risk via the short-range airborne route Jia, Wei Wei, Jianjian Cheng, Pan Wang, Qun Li, Yuguo Build Environ Article Leading health authorities have suggested short-range airborne transmission as a major route of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, there is no simple method to assess the short-range airborne infection risk or identify its governing parameters. We proposed a short-range airborne infection risk assessment model based on the continuum model and two-stage jet model. The effects of ventilation, physical distance and activity intensity on the short-range airborne exposure were studied systematically. The results suggested that increasing physical distance and ventilation reduced short-range airborne exposure and infection risk. However, a diminishing return phenomenon was observed when the ventilation rate or physical distance was beyond a certain threshold. When the infectious quantum concentration was less than 1 quantum/L at the mouth, our newly defined threshold distance and threshold ventilation rate were independent of quantum concentration. We estimated threshold distances of 0.59, 1.1, 1.7 and 2.6 m for sedentary/passive, light, moderate and intense activities, respectively. At these distances, the threshold ventilation was estimated to be 8, 20, 43, and 83 L/s per person, respectively. The findings show that both physical distancing and adequate ventilation are essential for minimising infection risk, especially in high-intensity activity or densely populated spaces. Elsevier Ltd. 2022-07-01 2022-05-10 /pmc/articles/PMC9085449/ /pubmed/35574565 http://dx.doi.org/10.1016/j.buildenv.2022.109166 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Jia, Wei
Wei, Jianjian
Cheng, Pan
Wang, Qun
Li, Yuguo
Exposure and respiratory infection risk via the short-range airborne route
title Exposure and respiratory infection risk via the short-range airborne route
title_full Exposure and respiratory infection risk via the short-range airborne route
title_fullStr Exposure and respiratory infection risk via the short-range airborne route
title_full_unstemmed Exposure and respiratory infection risk via the short-range airborne route
title_short Exposure and respiratory infection risk via the short-range airborne route
title_sort exposure and respiratory infection risk via the short-range airborne route
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085449/
https://www.ncbi.nlm.nih.gov/pubmed/35574565
http://dx.doi.org/10.1016/j.buildenv.2022.109166
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