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Development of an Fe(3)O(4)@Cu silicate based sensing platform for the electrochemical sensing of dopamine

Abnormal levels of dopamine (DA) in body fluids is an indication of serious health issues, hence development of highly sensitive platforms for the precise detection of DA is highly essential. Herein, we demonstrate an Fe(3)O(4)@Cu silicate based electrochemical sensing platform for the detection of...

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Autores principales: Das, Ashok Kumar, Kuchi, Rambabu, Van, Phuoc Cao, Sohn, Youngku, Jeong, Jong-Ryul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085485/
https://www.ncbi.nlm.nih.gov/pubmed/35548759
http://dx.doi.org/10.1039/c8ra05885g
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author Das, Ashok Kumar
Kuchi, Rambabu
Van, Phuoc Cao
Sohn, Youngku
Jeong, Jong-Ryul
author_facet Das, Ashok Kumar
Kuchi, Rambabu
Van, Phuoc Cao
Sohn, Youngku
Jeong, Jong-Ryul
author_sort Das, Ashok Kumar
collection PubMed
description Abnormal levels of dopamine (DA) in body fluids is an indication of serious health issues, hence development of highly sensitive platforms for the precise detection of DA is highly essential. Herein, we demonstrate an Fe(3)O(4)@Cu silicate based electrochemical sensing platform for the detection of DA. Morphology and BET analysis shows the formation of ∼320 nm sized sea urchin-like Fe(3)O(4)@Cu silicate core–shell nanostructures with a 174.5 m(2) g(−1) surface area. Compared to Fe(3)O(4) and Fe(3)O(4)@SiO(2), the Fe(3)O(4)@Cu silicate urchins delivered enhanced performance towards the electrochemical sensing of DA in neutral pH. The Fe(3)O(4)@Cu silicate sensor has a 1.37 μA μM(−1) cm(−2) sensitivity, 100–700 μM linear range and 3.2 μM limit of detection (LOD). In addition, the proposed Fe(3)O(4)@Cu silicate DA sensor also has good stability, selectivity, reproducibility and repeatability. The presence of Cu in Fe(3)O(4)@Cu silicate and the negatively charged surface of the Cu silicate shell play a vital role in achieving high selectivity and sensitivity during DA sensing. The current investigation not only represents the development of a highly selective DA sensor but also directs towards the possibility for the fabrication of other Cu silicate based core–shell nanostructures for the precise detection of DA.
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spelling pubmed-90854852022-05-10 Development of an Fe(3)O(4)@Cu silicate based sensing platform for the electrochemical sensing of dopamine Das, Ashok Kumar Kuchi, Rambabu Van, Phuoc Cao Sohn, Youngku Jeong, Jong-Ryul RSC Adv Chemistry Abnormal levels of dopamine (DA) in body fluids is an indication of serious health issues, hence development of highly sensitive platforms for the precise detection of DA is highly essential. Herein, we demonstrate an Fe(3)O(4)@Cu silicate based electrochemical sensing platform for the detection of DA. Morphology and BET analysis shows the formation of ∼320 nm sized sea urchin-like Fe(3)O(4)@Cu silicate core–shell nanostructures with a 174.5 m(2) g(−1) surface area. Compared to Fe(3)O(4) and Fe(3)O(4)@SiO(2), the Fe(3)O(4)@Cu silicate urchins delivered enhanced performance towards the electrochemical sensing of DA in neutral pH. The Fe(3)O(4)@Cu silicate sensor has a 1.37 μA μM(−1) cm(−2) sensitivity, 100–700 μM linear range and 3.2 μM limit of detection (LOD). In addition, the proposed Fe(3)O(4)@Cu silicate DA sensor also has good stability, selectivity, reproducibility and repeatability. The presence of Cu in Fe(3)O(4)@Cu silicate and the negatively charged surface of the Cu silicate shell play a vital role in achieving high selectivity and sensitivity during DA sensing. The current investigation not only represents the development of a highly selective DA sensor but also directs towards the possibility for the fabrication of other Cu silicate based core–shell nanostructures for the precise detection of DA. The Royal Society of Chemistry 2018-09-04 /pmc/articles/PMC9085485/ /pubmed/35548759 http://dx.doi.org/10.1039/c8ra05885g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Das, Ashok Kumar
Kuchi, Rambabu
Van, Phuoc Cao
Sohn, Youngku
Jeong, Jong-Ryul
Development of an Fe(3)O(4)@Cu silicate based sensing platform for the electrochemical sensing of dopamine
title Development of an Fe(3)O(4)@Cu silicate based sensing platform for the electrochemical sensing of dopamine
title_full Development of an Fe(3)O(4)@Cu silicate based sensing platform for the electrochemical sensing of dopamine
title_fullStr Development of an Fe(3)O(4)@Cu silicate based sensing platform for the electrochemical sensing of dopamine
title_full_unstemmed Development of an Fe(3)O(4)@Cu silicate based sensing platform for the electrochemical sensing of dopamine
title_short Development of an Fe(3)O(4)@Cu silicate based sensing platform for the electrochemical sensing of dopamine
title_sort development of an fe(3)o(4)@cu silicate based sensing platform for the electrochemical sensing of dopamine
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085485/
https://www.ncbi.nlm.nih.gov/pubmed/35548759
http://dx.doi.org/10.1039/c8ra05885g
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