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A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells
A new fluorescent probe based on pyrazolo[1,5-a]pyridine was synthesized and used to monitor the pH in cells. This probe exhibited a fast response to acidic pH (less than 10 s), a high quantum yield (φ = 0.64), and high selectivity and sensitivity. The response mechanism of the fluorescent probes re...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085528/ https://www.ncbi.nlm.nih.gov/pubmed/35548712 http://dx.doi.org/10.1039/c8ra06191b |
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author | Zhang, Ping Lv, Huaying Duan, Guiyun Dong, Jian Ge, Yanqing |
author_facet | Zhang, Ping Lv, Huaying Duan, Guiyun Dong, Jian Ge, Yanqing |
author_sort | Zhang, Ping |
collection | PubMed |
description | A new fluorescent probe based on pyrazolo[1,5-a]pyridine was synthesized and used to monitor the pH in cells. This probe exhibited a fast response to acidic pH (less than 10 s), a high quantum yield (φ = 0.64), and high selectivity and sensitivity. The response mechanism of the fluorescent probes relies on the ICT change. |
format | Online Article Text |
id | pubmed-9085528 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-90855282022-05-10 A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells Zhang, Ping Lv, Huaying Duan, Guiyun Dong, Jian Ge, Yanqing RSC Adv Chemistry A new fluorescent probe based on pyrazolo[1,5-a]pyridine was synthesized and used to monitor the pH in cells. This probe exhibited a fast response to acidic pH (less than 10 s), a high quantum yield (φ = 0.64), and high selectivity and sensitivity. The response mechanism of the fluorescent probes relies on the ICT change. The Royal Society of Chemistry 2018-08-31 /pmc/articles/PMC9085528/ /pubmed/35548712 http://dx.doi.org/10.1039/c8ra06191b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Zhang, Ping Lv, Huaying Duan, Guiyun Dong, Jian Ge, Yanqing A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells |
title | A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells |
title_full | A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells |
title_fullStr | A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells |
title_full_unstemmed | A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells |
title_short | A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells |
title_sort | novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect ph in cells |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085528/ https://www.ncbi.nlm.nih.gov/pubmed/35548712 http://dx.doi.org/10.1039/c8ra06191b |
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