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The effect of chlorhexidine on Acinetobacter baumannii in intensive care units
BACKGROUND AND OBJECTIVES: Measures to prevent the emergence of hospital-acquired infections (HAIs) include a daily bath with chlorhexidine gluconate (CHG). The aim of this study was to determine the effect of patients bathing daily with CHG on the bacterial colonization on patient surfaces, environ...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085541/ https://www.ncbi.nlm.nih.gov/pubmed/35664715 http://dx.doi.org/10.18502/ijm.v14i1.8796 |
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author | Martinez-Resendez, Michel F. Cruz-López, Flora Gaona-Chávez, Natalia Camacho-Ortiz, Adrián Mercado-Longoria, Roberto Flores-Treviño, Samantha Bocanegra-Ibarias, Paola Garza-González, Elvira |
author_facet | Martinez-Resendez, Michel F. Cruz-López, Flora Gaona-Chávez, Natalia Camacho-Ortiz, Adrián Mercado-Longoria, Roberto Flores-Treviño, Samantha Bocanegra-Ibarias, Paola Garza-González, Elvira |
author_sort | Martinez-Resendez, Michel F. |
collection | PubMed |
description | BACKGROUND AND OBJECTIVES: Measures to prevent the emergence of hospital-acquired infections (HAIs) include a daily bath with chlorhexidine gluconate (CHG). The aim of this study was to determine the effect of patients bathing daily with CHG on the bacterial colonization on patient surfaces, environmental surrounding areas, and attending healthcare workers (HCWs). MATERIALS AND METHODS: Patients were randomized by a 1:1 in two groups. Patients in group 1 were bathed daily with CHG; patients in group 2 were bathed with a placebo. Microbiological sampling of patients, environment, and HCWs were carried out on days 0, 3, and 10. The clonal relatedness of selected isolates collected was determined through pulsed-field gel electrophoresis. Clinical and demographic data were obtained from medical files. RESULTS: Thirty-three patients were included (18 in group 1 and 15 in group 2). The more common species was Acinetobacter baumannii (n=144), followed by Klebsiella pneumoniae (n=81). A. baumannii was isolated more frequently on environmental surfaces in group 2 than group 1 (day 0 vs. day 3 vs. day 10; p = 0.0388). Twelve clones of A. baumannii were detected, with predominant clone A detected in patients and environmental surfaces. No pathogens were detected in HCWs. CONCLUSION: Our data support that CHG bathing decreases A. baumannii surviving on the environmental surfaces of critically ill patients. |
format | Online Article Text |
id | pubmed-9085541 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-90855412022-06-04 The effect of chlorhexidine on Acinetobacter baumannii in intensive care units Martinez-Resendez, Michel F. Cruz-López, Flora Gaona-Chávez, Natalia Camacho-Ortiz, Adrián Mercado-Longoria, Roberto Flores-Treviño, Samantha Bocanegra-Ibarias, Paola Garza-González, Elvira Iran J Microbiol Original Article BACKGROUND AND OBJECTIVES: Measures to prevent the emergence of hospital-acquired infections (HAIs) include a daily bath with chlorhexidine gluconate (CHG). The aim of this study was to determine the effect of patients bathing daily with CHG on the bacterial colonization on patient surfaces, environmental surrounding areas, and attending healthcare workers (HCWs). MATERIALS AND METHODS: Patients were randomized by a 1:1 in two groups. Patients in group 1 were bathed daily with CHG; patients in group 2 were bathed with a placebo. Microbiological sampling of patients, environment, and HCWs were carried out on days 0, 3, and 10. The clonal relatedness of selected isolates collected was determined through pulsed-field gel electrophoresis. Clinical and demographic data were obtained from medical files. RESULTS: Thirty-three patients were included (18 in group 1 and 15 in group 2). The more common species was Acinetobacter baumannii (n=144), followed by Klebsiella pneumoniae (n=81). A. baumannii was isolated more frequently on environmental surfaces in group 2 than group 1 (day 0 vs. day 3 vs. day 10; p = 0.0388). Twelve clones of A. baumannii were detected, with predominant clone A detected in patients and environmental surfaces. No pathogens were detected in HCWs. CONCLUSION: Our data support that CHG bathing decreases A. baumannii surviving on the environmental surfaces of critically ill patients. Tehran University of Medical Sciences 2022-02 /pmc/articles/PMC9085541/ /pubmed/35664715 http://dx.doi.org/10.18502/ijm.v14i1.8796 Text en Copyright © 2022 The Authors. Published by Tehran University of Medical Sciences https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited. |
spellingShingle | Original Article Martinez-Resendez, Michel F. Cruz-López, Flora Gaona-Chávez, Natalia Camacho-Ortiz, Adrián Mercado-Longoria, Roberto Flores-Treviño, Samantha Bocanegra-Ibarias, Paola Garza-González, Elvira The effect of chlorhexidine on Acinetobacter baumannii in intensive care units |
title | The effect of chlorhexidine on Acinetobacter baumannii in intensive care units |
title_full | The effect of chlorhexidine on Acinetobacter baumannii in intensive care units |
title_fullStr | The effect of chlorhexidine on Acinetobacter baumannii in intensive care units |
title_full_unstemmed | The effect of chlorhexidine on Acinetobacter baumannii in intensive care units |
title_short | The effect of chlorhexidine on Acinetobacter baumannii in intensive care units |
title_sort | effect of chlorhexidine on acinetobacter baumannii in intensive care units |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085541/ https://www.ncbi.nlm.nih.gov/pubmed/35664715 http://dx.doi.org/10.18502/ijm.v14i1.8796 |
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