Detection of SO(2) derivatives using a new chalco-coumarin derivative in cationic micellar media: application to real samples

A new probe (E)-7-(diethylamino)-3-(3-(thiophen-2-yl)acryloyl)-2H-chromen-2-one (ChC16) was synthesized and studied as a turn-on fluorescent probe, based on a Michael addition mechanism for sensing SO(2) derivatives, which is favored in the presence of cationic micellar media such as cetylpyridinium...

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Detalles Bibliográficos
Autores principales: Gómez, Marisol, Aliaga, Margarita E., Arancibia, Verónica, Moya, Alexis, Segura, Camilo, Nuñez, Marco T., Aguirre, Pabla, Nagles, Edgar, García-Beltrán, Olimpo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085600/
https://www.ncbi.nlm.nih.gov/pubmed/35548216
http://dx.doi.org/10.1039/c8ra04526g
Descripción
Sumario:A new probe (E)-7-(diethylamino)-3-(3-(thiophen-2-yl)acryloyl)-2H-chromen-2-one (ChC16) was synthesized and studied as a turn-on fluorescent probe, based on a Michael addition mechanism for sensing SO(2) derivatives, which is favored in the presence of cationic micellar media such as cetylpyridinium bromide (CPB). The probe showed high selectivity and sensitivity toward bisulfite over other anions and biothiols, including cysteine (Cys), homocysteine (Hcy) and glutathione (GSH), with a detection limit of 240 nM. Moreover, the probe showed great potential for its practical application in the detection of bisulfite in real samples, such as dry white wine, and in bioimaging.

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