Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii

Polyellisin (1), an unprecedented polyketide possessing a tricyclic system sharing a spiroketal carbon, was isolated from cultures of the basidiomycete Polyporus ellisii. The structure with absolute configuration was elucidated by means of spectroscopic methods and the single crystal X-ray diffracti...

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Autores principales: Wang, Shuang, Li, Zheng-Hui, Ai, Hong-Lian, He, Juan, Feng, Tao, Liu, Ji-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085629/
https://www.ncbi.nlm.nih.gov/pubmed/35548250
http://dx.doi.org/10.1039/c8ra06544f
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author Wang, Shuang
Li, Zheng-Hui
Ai, Hong-Lian
He, Juan
Feng, Tao
Liu, Ji-Kai
author_facet Wang, Shuang
Li, Zheng-Hui
Ai, Hong-Lian
He, Juan
Feng, Tao
Liu, Ji-Kai
author_sort Wang, Shuang
collection PubMed
description Polyellisin (1), an unprecedented polyketide possessing a tricyclic system sharing a spiroketal carbon, was isolated from cultures of the basidiomycete Polyporus ellisii. The structure with absolute configuration was elucidated by means of spectroscopic methods and the single crystal X-ray diffraction. Polyellisin showed NO production inhibition with an IC(50) value of 17.2 μM.
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spelling pubmed-90856292022-05-10 Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii Wang, Shuang Li, Zheng-Hui Ai, Hong-Lian He, Juan Feng, Tao Liu, Ji-Kai RSC Adv Chemistry Polyellisin (1), an unprecedented polyketide possessing a tricyclic system sharing a spiroketal carbon, was isolated from cultures of the basidiomycete Polyporus ellisii. The structure with absolute configuration was elucidated by means of spectroscopic methods and the single crystal X-ray diffraction. Polyellisin showed NO production inhibition with an IC(50) value of 17.2 μM. The Royal Society of Chemistry 2018-09-10 /pmc/articles/PMC9085629/ /pubmed/35548250 http://dx.doi.org/10.1039/c8ra06544f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Wang, Shuang
Li, Zheng-Hui
Ai, Hong-Lian
He, Juan
Feng, Tao
Liu, Ji-Kai
Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii
title Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii
title_full Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii
title_fullStr Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii
title_full_unstemmed Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii
title_short Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii
title_sort polyellisin, a novel polyketide from cultures of the basidiomycete polyporus ellisii
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085629/
https://www.ncbi.nlm.nih.gov/pubmed/35548250
http://dx.doi.org/10.1039/c8ra06544f
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