B(C(6)F(5))(3) catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols

An efficient and general method of nucleophilic substitution of benzylic alcohols catalyzed by non-metallic Lewis acid B(C(6)F(5))(3) was developed. The reaction could be carried out under mild conditions and more than 35 examples of ethers, thioethers and triarylmethanes were constructed in high yi...

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Detalles Bibliográficos
Autores principales: Meng, Shan-Shui, Wang, Qian, Huang, Gong-Bin, Lin, Li-Rong, Zhao, Jun-Ling, Chan, Albert S. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085633/
https://www.ncbi.nlm.nih.gov/pubmed/35548750
http://dx.doi.org/10.1039/c8ra05811c
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author Meng, Shan-Shui
Wang, Qian
Huang, Gong-Bin
Lin, Li-Rong
Zhao, Jun-Ling
Chan, Albert S. C.
author_facet Meng, Shan-Shui
Wang, Qian
Huang, Gong-Bin
Lin, Li-Rong
Zhao, Jun-Ling
Chan, Albert S. C.
author_sort Meng, Shan-Shui
collection PubMed
description An efficient and general method of nucleophilic substitution of benzylic alcohols catalyzed by non-metallic Lewis acid B(C(6)F(5))(3) was developed. The reaction could be carried out under mild conditions and more than 35 examples of ethers, thioethers and triarylmethanes were constructed in high yields. Some bioactive organic molecules were synthesized directly using the methods.
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spelling pubmed-90856332022-05-10 B(C(6)F(5))(3) catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols Meng, Shan-Shui Wang, Qian Huang, Gong-Bin Lin, Li-Rong Zhao, Jun-Ling Chan, Albert S. C. RSC Adv Chemistry An efficient and general method of nucleophilic substitution of benzylic alcohols catalyzed by non-metallic Lewis acid B(C(6)F(5))(3) was developed. The reaction could be carried out under mild conditions and more than 35 examples of ethers, thioethers and triarylmethanes were constructed in high yields. Some bioactive organic molecules were synthesized directly using the methods. The Royal Society of Chemistry 2018-09-03 /pmc/articles/PMC9085633/ /pubmed/35548750 http://dx.doi.org/10.1039/c8ra05811c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Meng, Shan-Shui
Wang, Qian
Huang, Gong-Bin
Lin, Li-Rong
Zhao, Jun-Ling
Chan, Albert S. C.
B(C(6)F(5))(3) catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols
title B(C(6)F(5))(3) catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols
title_full B(C(6)F(5))(3) catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols
title_fullStr B(C(6)F(5))(3) catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols
title_full_unstemmed B(C(6)F(5))(3) catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols
title_short B(C(6)F(5))(3) catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols
title_sort b(c(6)f(5))(3) catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing c–o, c–s and c–c bonds from benzylic alcohols
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085633/
https://www.ncbi.nlm.nih.gov/pubmed/35548750
http://dx.doi.org/10.1039/c8ra05811c
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