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Association between metabolic syndrome components and chronic kidney disease among 37,533 old Chinese individuals

BACKGROUND: Chronic kidney disease (CKD) has become a worldwide health problem among aging populations. However, epidemiological information on Chinese elderly people with CKD is still lacking. This study aimed to investigate the epidemiological features and associated risk factors of CKD in aging p...

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Autores principales: Xu, Lingling, Liu, Jin, Li, Dongling, Yang, Hua, Zhou, Yang, Yang, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085695/
https://www.ncbi.nlm.nih.gov/pubmed/34671893
http://dx.doi.org/10.1007/s11255-021-03013-3
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author Xu, Lingling
Liu, Jin
Li, Dongling
Yang, Hua
Zhou, Yang
Yang, Junwei
author_facet Xu, Lingling
Liu, Jin
Li, Dongling
Yang, Hua
Zhou, Yang
Yang, Junwei
author_sort Xu, Lingling
collection PubMed
description BACKGROUND: Chronic kidney disease (CKD) has become a worldwide health problem among aging populations. However, epidemiological information on Chinese elderly people with CKD is still lacking. This study aimed to investigate the epidemiological features and associated risk factors of CKD in aging population in China. METHODS: In this cross-sectional study, a total of 37,533 individuals aged ≥ 65 years were enrolled in Binhai from January to December 2018. The crude and standardized prevalence of CKD were calculated. Associations of metabolism-related indicators with CKD were examined using univariate and multivariate analyses. RESULTS: The overall prevalence of CKD was 17.7% (95% confidence interval 17.3–18.1%) in this Chinese elderly population. The prevalence was 17.5% among men (95% CI 17.0–18.1%) and 17.8% among women (95% CI 17.3–18.4%). The mean eGFR was 84.22 (SD ± 12.87) mL/min/1.73 m(2), with the median value higher for women than for men. CONCLUSION: Our study shows a high prevalence of CKD among Chinese elderly population. Aging, pre-HTN, HTN, elevated triglyceride, and FBG were associated with the risk of CKD. More attention should be paid to metabolic diseases to prevent CKD in the elderly.
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spelling pubmed-90856952022-05-11 Association between metabolic syndrome components and chronic kidney disease among 37,533 old Chinese individuals Xu, Lingling Liu, Jin Li, Dongling Yang, Hua Zhou, Yang Yang, Junwei Int Urol Nephrol Nephrology - Original Paper BACKGROUND: Chronic kidney disease (CKD) has become a worldwide health problem among aging populations. However, epidemiological information on Chinese elderly people with CKD is still lacking. This study aimed to investigate the epidemiological features and associated risk factors of CKD in aging population in China. METHODS: In this cross-sectional study, a total of 37,533 individuals aged ≥ 65 years were enrolled in Binhai from January to December 2018. The crude and standardized prevalence of CKD were calculated. Associations of metabolism-related indicators with CKD were examined using univariate and multivariate analyses. RESULTS: The overall prevalence of CKD was 17.7% (95% confidence interval 17.3–18.1%) in this Chinese elderly population. The prevalence was 17.5% among men (95% CI 17.0–18.1%) and 17.8% among women (95% CI 17.3–18.4%). The mean eGFR was 84.22 (SD ± 12.87) mL/min/1.73 m(2), with the median value higher for women than for men. CONCLUSION: Our study shows a high prevalence of CKD among Chinese elderly population. Aging, pre-HTN, HTN, elevated triglyceride, and FBG were associated with the risk of CKD. More attention should be paid to metabolic diseases to prevent CKD in the elderly. Springer Netherlands 2021-10-21 2022 /pmc/articles/PMC9085695/ /pubmed/34671893 http://dx.doi.org/10.1007/s11255-021-03013-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Nephrology - Original Paper
Xu, Lingling
Liu, Jin
Li, Dongling
Yang, Hua
Zhou, Yang
Yang, Junwei
Association between metabolic syndrome components and chronic kidney disease among 37,533 old Chinese individuals
title Association between metabolic syndrome components and chronic kidney disease among 37,533 old Chinese individuals
title_full Association between metabolic syndrome components and chronic kidney disease among 37,533 old Chinese individuals
title_fullStr Association between metabolic syndrome components and chronic kidney disease among 37,533 old Chinese individuals
title_full_unstemmed Association between metabolic syndrome components and chronic kidney disease among 37,533 old Chinese individuals
title_short Association between metabolic syndrome components and chronic kidney disease among 37,533 old Chinese individuals
title_sort association between metabolic syndrome components and chronic kidney disease among 37,533 old chinese individuals
topic Nephrology - Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085695/
https://www.ncbi.nlm.nih.gov/pubmed/34671893
http://dx.doi.org/10.1007/s11255-021-03013-3
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