The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers

N(6)-methyladenosine (m(6)A) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a la...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jingwen, Zhao, Wei, Zhang, Leyu, Wang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085772/
https://www.ncbi.nlm.nih.gov/pubmed/35534472
http://dx.doi.org/10.1038/s41420-022-01050-0
Descripción
Sumario:N(6)-methyladenosine (m(6)A) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a large number of vital biological progressions. With the great improvement of molecular biology, m(6)A and lncRNAs are attracting more attention from researchers and scholars. In this review, we overview the current status of m(6)A and lncRNAs based on the latest research, and propose some viewpoints for future research perspectives.

Ejemplares similares