The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers

N(6)-methyladenosine (m(6)A) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a la...

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Detalles Bibliográficos
Autores principales: Liu, Jingwen, Zhao, Wei, Zhang, Leyu, Wang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085772/
https://www.ncbi.nlm.nih.gov/pubmed/35534472
http://dx.doi.org/10.1038/s41420-022-01050-0
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author Liu, Jingwen
Zhao, Wei
Zhang, Leyu
Wang, Xi
author_facet Liu, Jingwen
Zhao, Wei
Zhang, Leyu
Wang, Xi
author_sort Liu, Jingwen
collection PubMed
description N(6)-methyladenosine (m(6)A) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a large number of vital biological progressions. With the great improvement of molecular biology, m(6)A and lncRNAs are attracting more attention from researchers and scholars. In this review, we overview the current status of m(6)A and lncRNAs based on the latest research, and propose some viewpoints for future research perspectives.
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spelling pubmed-90857722022-05-11 The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers Liu, Jingwen Zhao, Wei Zhang, Leyu Wang, Xi Cell Death Discov Review Article N(6)-methyladenosine (m(6)A) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a large number of vital biological progressions. With the great improvement of molecular biology, m(6)A and lncRNAs are attracting more attention from researchers and scholars. In this review, we overview the current status of m(6)A and lncRNAs based on the latest research, and propose some viewpoints for future research perspectives. Nature Publishing Group UK 2022-05-09 /pmc/articles/PMC9085772/ /pubmed/35534472 http://dx.doi.org/10.1038/s41420-022-01050-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Liu, Jingwen
Zhao, Wei
Zhang, Leyu
Wang, Xi
The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers
title The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers
title_full The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers
title_fullStr The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers
title_full_unstemmed The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers
title_short The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers
title_sort emerging roles of n6-methyladenosine (m6a)-modified long non-coding rnas in human cancers
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085772/
https://www.ncbi.nlm.nih.gov/pubmed/35534472
http://dx.doi.org/10.1038/s41420-022-01050-0
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