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TAVI-CT score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation
Transcatheter aortic valve implantation (TAVI) requires thorough preprocedural planning with non-invasive imaging, including computed tomography (CT). The plethora of details obtained with thoraco-abdominal CT represents a challenge for accurate and synthetic decision-making. We devised and tested a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085825/ https://www.ncbi.nlm.nih.gov/pubmed/35534616 http://dx.doi.org/10.1038/s41598-022-11788-3 |
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author | Corcione, Nicola Morello, Alberto Ferraro, Paolo Cimmino, Michele Albanese, Michele Pepe, Martino Nestola, Palma Luisa Giordano, Salvatore Bardi, Luca Biondi-Zoccai, Giuseppe Giordano, Arturo |
author_facet | Corcione, Nicola Morello, Alberto Ferraro, Paolo Cimmino, Michele Albanese, Michele Pepe, Martino Nestola, Palma Luisa Giordano, Salvatore Bardi, Luca Biondi-Zoccai, Giuseppe Giordano, Arturo |
author_sort | Corcione, Nicola |
collection | PubMed |
description | Transcatheter aortic valve implantation (TAVI) requires thorough preprocedural planning with non-invasive imaging, including computed tomography (CT). The plethora of details obtained with thoraco-abdominal CT represents a challenge for accurate and synthetic decision-making. We devised and tested a comprehensive score suitable to summarize CT exams when planning TAVI. An original comprehensive scoring system (TAVI-CT score) was devised, including details on cardiac, aortic, iliac and femoral artery features. The score was applied to a prospectively collected series of patients undergoing TAVI at our institution, driving decision making on access and prosthesis choice. Different TAVI-CT score groups were compared in terms of procedural success, acute complications, and early clinical outcomes. We included a total of 200 undergoing TAVI between February 2020 and May 2021, with 74 (37.0%) having a low (0–2) TAVI-CT score, 50 (25.0%) having a moderate (3) TAVI-CT score, and 76 (38.0%) having a high (≥ 4) TAVI-CT score. Male gender was the only non-CT variable significantly associated with the TAVI-CT score (p = 0.001). As expected, access choice differed significantly across TAVI-CT scores (p = 0.009), as was device choice, with Portico more favored and Allegra less favored in the highest TAVI-CT score group (p = 0.036). Acute outcomes were similar in the 3 groups, including device and procedural success rates (respectively p = 0.717 and p = 1). One-month follow-up showed similar rates of death, myocardial infarction, stroke, and bleeding, as well as of a composite safety endpoint (all p > 0.05). However, vascular complications were significantly more common in the highest TAVI-CT score group (p = 0.041). The TAVI-CT score is a simple scoring system that could be routinely applied to CT imaging for TAVI planning, if the present hypothesis-generating findings are confirmed in larger prospective studies. |
format | Online Article Text |
id | pubmed-9085825 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-90858252022-05-11 TAVI-CT score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation Corcione, Nicola Morello, Alberto Ferraro, Paolo Cimmino, Michele Albanese, Michele Pepe, Martino Nestola, Palma Luisa Giordano, Salvatore Bardi, Luca Biondi-Zoccai, Giuseppe Giordano, Arturo Sci Rep Article Transcatheter aortic valve implantation (TAVI) requires thorough preprocedural planning with non-invasive imaging, including computed tomography (CT). The plethora of details obtained with thoraco-abdominal CT represents a challenge for accurate and synthetic decision-making. We devised and tested a comprehensive score suitable to summarize CT exams when planning TAVI. An original comprehensive scoring system (TAVI-CT score) was devised, including details on cardiac, aortic, iliac and femoral artery features. The score was applied to a prospectively collected series of patients undergoing TAVI at our institution, driving decision making on access and prosthesis choice. Different TAVI-CT score groups were compared in terms of procedural success, acute complications, and early clinical outcomes. We included a total of 200 undergoing TAVI between February 2020 and May 2021, with 74 (37.0%) having a low (0–2) TAVI-CT score, 50 (25.0%) having a moderate (3) TAVI-CT score, and 76 (38.0%) having a high (≥ 4) TAVI-CT score. Male gender was the only non-CT variable significantly associated with the TAVI-CT score (p = 0.001). As expected, access choice differed significantly across TAVI-CT scores (p = 0.009), as was device choice, with Portico more favored and Allegra less favored in the highest TAVI-CT score group (p = 0.036). Acute outcomes were similar in the 3 groups, including device and procedural success rates (respectively p = 0.717 and p = 1). One-month follow-up showed similar rates of death, myocardial infarction, stroke, and bleeding, as well as of a composite safety endpoint (all p > 0.05). However, vascular complications were significantly more common in the highest TAVI-CT score group (p = 0.041). The TAVI-CT score is a simple scoring system that could be routinely applied to CT imaging for TAVI planning, if the present hypothesis-generating findings are confirmed in larger prospective studies. Nature Publishing Group UK 2022-05-09 /pmc/articles/PMC9085825/ /pubmed/35534616 http://dx.doi.org/10.1038/s41598-022-11788-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Corcione, Nicola Morello, Alberto Ferraro, Paolo Cimmino, Michele Albanese, Michele Pepe, Martino Nestola, Palma Luisa Giordano, Salvatore Bardi, Luca Biondi-Zoccai, Giuseppe Giordano, Arturo TAVI-CT score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation |
title | TAVI-CT score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation |
title_full | TAVI-CT score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation |
title_fullStr | TAVI-CT score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation |
title_full_unstemmed | TAVI-CT score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation |
title_short | TAVI-CT score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation |
title_sort | tavi-ct score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085825/ https://www.ncbi.nlm.nih.gov/pubmed/35534616 http://dx.doi.org/10.1038/s41598-022-11788-3 |
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