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Functional and structural characterization of interactions between opposite subunits in HCN pacemaker channels

Hyperpolarization-activated and cyclic nucleotide (HCN) modulated channels are tetrameric cation channels. In each of the four subunits, the intracellular cyclic nucleotide-binding domain (CNBD) is coupled to the transmembrane domain via a helical structure, the C-linker. High-resolution channel str...

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Detalles Bibliográficos
Autores principales:	Kondapuram, Mahesh, Frieg, Benedikt, Yüksel, Sezin, Schwabe, Tina, Sattler, Christian, Lelle, Marco, Schweinitz, Andrea, Schmauder, Ralf, Benndorf, Klaus, Gohlke, Holger, Kusch, Jana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085832/ https://www.ncbi.nlm.nih.gov/pubmed/35534535 http://dx.doi.org/10.1038/s42003-022-03360-6

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