KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines

A one-pot approach to substituted 1,2,4-triazolo[4,3-a]pyridines has been developed that is based on a KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines. This transition-metal-free procedure was highly efficient and shows good economical and environmental advantages.

Detalles Bibliográficos
Autores principales: Yang, De-Suo, Wang, Juan, Gao, Peng, Bai, Zi-Jing, Duan, Dong-Zhu, Fan, Ming-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086216/
https://www.ncbi.nlm.nih.gov/pubmed/35547701
http://dx.doi.org/10.1039/c8ra06215c
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author Yang, De-Suo
Wang, Juan
Gao, Peng
Bai, Zi-Jing
Duan, Dong-Zhu
Fan, Ming-Jin
author_facet Yang, De-Suo
Wang, Juan
Gao, Peng
Bai, Zi-Jing
Duan, Dong-Zhu
Fan, Ming-Jin
author_sort Yang, De-Suo
collection PubMed
description A one-pot approach to substituted 1,2,4-triazolo[4,3-a]pyridines has been developed that is based on a KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines. This transition-metal-free procedure was highly efficient and shows good economical and environmental advantages.
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spelling pubmed-90862162022-05-10 KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines Yang, De-Suo Wang, Juan Gao, Peng Bai, Zi-Jing Duan, Dong-Zhu Fan, Ming-Jin RSC Adv Chemistry A one-pot approach to substituted 1,2,4-triazolo[4,3-a]pyridines has been developed that is based on a KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines. This transition-metal-free procedure was highly efficient and shows good economical and environmental advantages. The Royal Society of Chemistry 2018-09-21 /pmc/articles/PMC9086216/ /pubmed/35547701 http://dx.doi.org/10.1039/c8ra06215c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Yang, De-Suo
Wang, Juan
Gao, Peng
Bai, Zi-Jing
Duan, Dong-Zhu
Fan, Ming-Jin
KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines
title KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines
title_full KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines
title_fullStr KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines
title_full_unstemmed KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines
title_short KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines
title_sort ki-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086216/
https://www.ncbi.nlm.nih.gov/pubmed/35547701
http://dx.doi.org/10.1039/c8ra06215c
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