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Unlocked nucleic acid modified primer-based enzymatic polymerization assay: towards allele-specific genotype detection of human platelet antigens

Accurate detection of single nucleotide polymorphisms (SNPs) is paramount for the appropriate therapeutic intervention of debilitating diseases associated with SNPs. However, in some cases current nucleic acid probes fail to detect allele-specific mutations, for example, human platelet antigens, HPA...

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Detalles Bibliográficos
Autores principales:	Le, Bao T., Hughes, Quintin, Rakesh, Shilpa, Baker, Ross, Jørgensen, Per T., Wengel, Jesper, Veedu, Rakesh N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086379/ https://www.ncbi.nlm.nih.gov/pubmed/35547719 http://dx.doi.org/10.1039/c8ra06050a

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