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Comparison of the physical and thermodynamic stability of amorphous azelnidipine and its coamorphous phase with piperazine
A major challenge in drug development is that the majority of drugs are water insoluble, and a powerful method to conquer this obstacle is to transfer a crystalline drug into its amorphous phase (AP) or coamorphous phase (CAP) with a coformer. In the present study, the physical and chemical stabilit...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086389/ https://www.ncbi.nlm.nih.gov/pubmed/35547669 http://dx.doi.org/10.1039/c8ra05535a |