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A Novel Antimalarial Metabolite in Erythrocyte From the Hydroxylation of Dihydroartemisinin by Cunninghamella elegans
Dihydroartemisinin (DHA) is a sesquiterpene endoperoxide with prominent antimalarial efficacy, which was discovered by Professor Youyou Tu through the reduction of artemisinin in the 1970s. It is always a challenging work for scientists to investigate the metabolites of DHA in the red blood cells du...
Autores principales: | Bai, Yue, Zhao, Yifan, Gao, Xinna, Zhang, Dong, Ma, Yue, Yang, Lan, Sun, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086495/ https://www.ncbi.nlm.nih.gov/pubmed/35559220 http://dx.doi.org/10.3389/fchem.2022.850133 |
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