Cargando…

Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey

Sensory prediction is considered an important element of mismatch negativity (MMN) whose reduction is well known in patients with schizophrenia. Omission MMN is a variant of the MMN which is elicited by the absence of a tone previously sequentially presented. Omission MMN can eliminate the effects o...

Descripción completa

Detalles Bibliográficos
Autores principales: Suda, Yuki, Tada, Mariko, Matsuo, Takeshi, Kawasaki, Keisuke, Saigusa, Takeshi, Ishida, Maho, Mitsui, Tetsuo, Kumano, Hironori, Kirihara, Kenji, Suzuki, Takafumi, Matsumoto, Kenji, Hasegawa, Isao, Kasai, Kiyoto, Uka, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086590/
https://www.ncbi.nlm.nih.gov/pubmed/35558420
http://dx.doi.org/10.3389/fpsyt.2022.557954
_version_ 1784704037756600320
author Suda, Yuki
Tada, Mariko
Matsuo, Takeshi
Kawasaki, Keisuke
Saigusa, Takeshi
Ishida, Maho
Mitsui, Tetsuo
Kumano, Hironori
Kirihara, Kenji
Suzuki, Takafumi
Matsumoto, Kenji
Hasegawa, Isao
Kasai, Kiyoto
Uka, Takanori
author_facet Suda, Yuki
Tada, Mariko
Matsuo, Takeshi
Kawasaki, Keisuke
Saigusa, Takeshi
Ishida, Maho
Mitsui, Tetsuo
Kumano, Hironori
Kirihara, Kenji
Suzuki, Takafumi
Matsumoto, Kenji
Hasegawa, Isao
Kasai, Kiyoto
Uka, Takanori
author_sort Suda, Yuki
collection PubMed
description Sensory prediction is considered an important element of mismatch negativity (MMN) whose reduction is well known in patients with schizophrenia. Omission MMN is a variant of the MMN which is elicited by the absence of a tone previously sequentially presented. Omission MMN can eliminate the effects of sound differences in typical oddball paradigms and affords the opportunity to identify prediction-related signals in the brain. Auditory predictions are thought to reflect bottom-up and top-down processing within hierarchically organized auditory areas. However, the communications between the various subregions of the auditory cortex and the prefrontal cortex that generate and communicate sensory prediction-related signals remain poorly understood. To explore how the frontal and temporal cortices communicate for the generation and propagation of such signals, we investigated the response in the omission paradigm using electrocorticogram (ECoG) electrodes implanted in the temporal, lateral prefrontal, and orbitofrontal cortices of macaque monkeys. We recorded ECoG data from three monkeys during the omission paradigm and examined the functional connectivity between the temporal and frontal cortices by calculating phase-locking values (PLVs). This revealed that theta- (4–8 Hz), alpha- (8–12 Hz), and low-beta- (12–25 Hz) band synchronization increased at tone onset between the higher auditory cortex and the frontal pole where an early omission response was observed in the event-related potential (ERP). These synchronizations were absent when the tone was omitted. Conversely, low-beta-band (12–25 Hz) oscillation then became stronger for tone omission than for tone presentation approximately 200 ms after tone onset. The results suggest that auditory input is propagated to the frontal pole via the higher auditory cortex and that a reciprocal network may be involved in the generation of auditory prediction and prediction error. As impairments of prediction may underlie MMN reduction in patients with schizophrenia, an aberrant hierarchical temporal-frontal network might be related to this pathological condition.
format Online
Article
Text
id pubmed-9086590
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-90865902022-05-11 Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey Suda, Yuki Tada, Mariko Matsuo, Takeshi Kawasaki, Keisuke Saigusa, Takeshi Ishida, Maho Mitsui, Tetsuo Kumano, Hironori Kirihara, Kenji Suzuki, Takafumi Matsumoto, Kenji Hasegawa, Isao Kasai, Kiyoto Uka, Takanori Front Psychiatry Psychiatry Sensory prediction is considered an important element of mismatch negativity (MMN) whose reduction is well known in patients with schizophrenia. Omission MMN is a variant of the MMN which is elicited by the absence of a tone previously sequentially presented. Omission MMN can eliminate the effects of sound differences in typical oddball paradigms and affords the opportunity to identify prediction-related signals in the brain. Auditory predictions are thought to reflect bottom-up and top-down processing within hierarchically organized auditory areas. However, the communications between the various subregions of the auditory cortex and the prefrontal cortex that generate and communicate sensory prediction-related signals remain poorly understood. To explore how the frontal and temporal cortices communicate for the generation and propagation of such signals, we investigated the response in the omission paradigm using electrocorticogram (ECoG) electrodes implanted in the temporal, lateral prefrontal, and orbitofrontal cortices of macaque monkeys. We recorded ECoG data from three monkeys during the omission paradigm and examined the functional connectivity between the temporal and frontal cortices by calculating phase-locking values (PLVs). This revealed that theta- (4–8 Hz), alpha- (8–12 Hz), and low-beta- (12–25 Hz) band synchronization increased at tone onset between the higher auditory cortex and the frontal pole where an early omission response was observed in the event-related potential (ERP). These synchronizations were absent when the tone was omitted. Conversely, low-beta-band (12–25 Hz) oscillation then became stronger for tone omission than for tone presentation approximately 200 ms after tone onset. The results suggest that auditory input is propagated to the frontal pole via the higher auditory cortex and that a reciprocal network may be involved in the generation of auditory prediction and prediction error. As impairments of prediction may underlie MMN reduction in patients with schizophrenia, an aberrant hierarchical temporal-frontal network might be related to this pathological condition. Frontiers Media S.A. 2022-04-26 /pmc/articles/PMC9086590/ /pubmed/35558420 http://dx.doi.org/10.3389/fpsyt.2022.557954 Text en Copyright © 2022 Suda, Tada, Matsuo, Kawasaki, Saigusa, Ishida, Mitsui, Kumano, Kirihara, Suzuki, Matsumoto, Hasegawa, Kasai and Uka. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Suda, Yuki
Tada, Mariko
Matsuo, Takeshi
Kawasaki, Keisuke
Saigusa, Takeshi
Ishida, Maho
Mitsui, Tetsuo
Kumano, Hironori
Kirihara, Kenji
Suzuki, Takafumi
Matsumoto, Kenji
Hasegawa, Isao
Kasai, Kiyoto
Uka, Takanori
Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey
title Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey
title_full Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey
title_fullStr Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey
title_full_unstemmed Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey
title_short Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey
title_sort prediction-related frontal-temporal network for omission mismatch activity in the macaque monkey
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086590/
https://www.ncbi.nlm.nih.gov/pubmed/35558420
http://dx.doi.org/10.3389/fpsyt.2022.557954
work_keys_str_mv AT sudayuki predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT tadamariko predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT matsuotakeshi predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT kawasakikeisuke predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT saigusatakeshi predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT ishidamaho predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT mitsuitetsuo predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT kumanohironori predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT kiriharakenji predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT suzukitakafumi predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT matsumotokenji predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT hasegawaisao predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT kasaikiyoto predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey
AT ukatakanori predictionrelatedfrontaltemporalnetworkforomissionmismatchactivityinthemacaquemonkey