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Rare occurrence of Guillain-Barré syndrome after Moderna vaccine

A Caucasian man in his 60s with a medical history significant for ruptured left middle cerebral artery aneurysm status post clipping 2005 with residual right eye blindness and right leg weakness with gait instability presented with loss of balance, weakness of his legs and fatigue for 3 days. No oth...

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Autores principales: Bijoy George, Tissa, Kainat, Aleesha, Pachika, Pranali Santhoshini, Arnold, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086602/
https://www.ncbi.nlm.nih.gov/pubmed/35534045
http://dx.doi.org/10.1136/bcr-2022-249749
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author Bijoy George, Tissa
Kainat, Aleesha
Pachika, Pranali Santhoshini
Arnold, Jonathan
author_facet Bijoy George, Tissa
Kainat, Aleesha
Pachika, Pranali Santhoshini
Arnold, Jonathan
author_sort Bijoy George, Tissa
collection PubMed
description A Caucasian man in his 60s with a medical history significant for ruptured left middle cerebral artery aneurysm status post clipping 2005 with residual right eye blindness and right leg weakness with gait instability presented with loss of balance, weakness of his legs and fatigue for 3 days. No other antecedent event was identified other than receiving Moderna COVID-19 vaccine 4 weeks before the presentation and 3 days before symptom onset. CT head and CT angiogram of the head and neck were performed and demonstrated no acute intracranial bleeding and no vascular abnormalities. With the findings of diffuse hyporeflexia and cerebrospinal fluid showing albumino-cytological dissociation, Guillain-Barré syndrome was high on the differentials. Electromyogram showed evidence of demyelination. He was treated with intravenous immune globulin (IVIG) and was discharged to rehab with complete symptom resolution.
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spelling pubmed-90866022022-05-20 Rare occurrence of Guillain-Barré syndrome after Moderna vaccine Bijoy George, Tissa Kainat, Aleesha Pachika, Pranali Santhoshini Arnold, Jonathan BMJ Case Rep Case Reports: Unusual presentation of more common disease/injury A Caucasian man in his 60s with a medical history significant for ruptured left middle cerebral artery aneurysm status post clipping 2005 with residual right eye blindness and right leg weakness with gait instability presented with loss of balance, weakness of his legs and fatigue for 3 days. No other antecedent event was identified other than receiving Moderna COVID-19 vaccine 4 weeks before the presentation and 3 days before symptom onset. CT head and CT angiogram of the head and neck were performed and demonstrated no acute intracranial bleeding and no vascular abnormalities. With the findings of diffuse hyporeflexia and cerebrospinal fluid showing albumino-cytological dissociation, Guillain-Barré syndrome was high on the differentials. Electromyogram showed evidence of demyelination. He was treated with intravenous immune globulin (IVIG) and was discharged to rehab with complete symptom resolution. BMJ Publishing Group 2022-05-09 /pmc/articles/PMC9086602/ /pubmed/35534045 http://dx.doi.org/10.1136/bcr-2022-249749 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.
spellingShingle Case Reports: Unusual presentation of more common disease/injury
Bijoy George, Tissa
Kainat, Aleesha
Pachika, Pranali Santhoshini
Arnold, Jonathan
Rare occurrence of Guillain-Barré syndrome after Moderna vaccine
title Rare occurrence of Guillain-Barré syndrome after Moderna vaccine
title_full Rare occurrence of Guillain-Barré syndrome after Moderna vaccine
title_fullStr Rare occurrence of Guillain-Barré syndrome after Moderna vaccine
title_full_unstemmed Rare occurrence of Guillain-Barré syndrome after Moderna vaccine
title_short Rare occurrence of Guillain-Barré syndrome after Moderna vaccine
title_sort rare occurrence of guillain-barré syndrome after moderna vaccine
topic Case Reports: Unusual presentation of more common disease/injury
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086602/
https://www.ncbi.nlm.nih.gov/pubmed/35534045
http://dx.doi.org/10.1136/bcr-2022-249749
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