Transition metal/Brønsted acid cooperative catalysis enabled facile synthesis of 8-hydroxyquinolines through one-pot reactions of ortho-aminophenol, aldehydes and alkynes

A convenient and straightforward three-component one-pot strategy has been developed for the synthesis of 8-hydroxyquinoline derivatives. Under the cooperative catalysis of silver(i) triflate and trifluoroacetic acid, ortho-aminophenol reacted with a range of aldehydes and alkynes under mild reactio...

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Detalles Bibliográficos
Autores principales: Yu, Shuyan, Wu, Jingxin, Lan, Hongbing, Xu, Hanwen, Shi, Xiaofei, Zhu, Xuewen, Yin, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086736/
https://www.ncbi.nlm.nih.gov/pubmed/35548801
http://dx.doi.org/10.1039/c8ra07212d
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author Yu, Shuyan
Wu, Jingxin
Lan, Hongbing
Xu, Hanwen
Shi, Xiaofei
Zhu, Xuewen
Yin, Zhigang
author_facet Yu, Shuyan
Wu, Jingxin
Lan, Hongbing
Xu, Hanwen
Shi, Xiaofei
Zhu, Xuewen
Yin, Zhigang
author_sort Yu, Shuyan
collection PubMed
description A convenient and straightforward three-component one-pot strategy has been developed for the synthesis of 8-hydroxyquinoline derivatives. Under the cooperative catalysis of silver(i) triflate and trifluoroacetic acid, ortho-aminophenol reacted with a range of aldehydes and alkynes under mild reactions, affording the corresponding 8-hydroxyquinoline derivatives with good to excellent yields. These transformations exhibited exceptional substrate generality and functional group compatibility.
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spelling pubmed-90867362022-05-10 Transition metal/Brønsted acid cooperative catalysis enabled facile synthesis of 8-hydroxyquinolines through one-pot reactions of ortho-aminophenol, aldehydes and alkynes Yu, Shuyan Wu, Jingxin Lan, Hongbing Xu, Hanwen Shi, Xiaofei Zhu, Xuewen Yin, Zhigang RSC Adv Chemistry A convenient and straightforward three-component one-pot strategy has been developed for the synthesis of 8-hydroxyquinoline derivatives. Under the cooperative catalysis of silver(i) triflate and trifluoroacetic acid, ortho-aminophenol reacted with a range of aldehydes and alkynes under mild reactions, affording the corresponding 8-hydroxyquinoline derivatives with good to excellent yields. These transformations exhibited exceptional substrate generality and functional group compatibility. The Royal Society of Chemistry 2018-10-03 /pmc/articles/PMC9086736/ /pubmed/35548801 http://dx.doi.org/10.1039/c8ra07212d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Yu, Shuyan
Wu, Jingxin
Lan, Hongbing
Xu, Hanwen
Shi, Xiaofei
Zhu, Xuewen
Yin, Zhigang
Transition metal/Brønsted acid cooperative catalysis enabled facile synthesis of 8-hydroxyquinolines through one-pot reactions of ortho-aminophenol, aldehydes and alkynes
title Transition metal/Brønsted acid cooperative catalysis enabled facile synthesis of 8-hydroxyquinolines through one-pot reactions of ortho-aminophenol, aldehydes and alkynes
title_full Transition metal/Brønsted acid cooperative catalysis enabled facile synthesis of 8-hydroxyquinolines through one-pot reactions of ortho-aminophenol, aldehydes and alkynes
title_fullStr Transition metal/Brønsted acid cooperative catalysis enabled facile synthesis of 8-hydroxyquinolines through one-pot reactions of ortho-aminophenol, aldehydes and alkynes
title_full_unstemmed Transition metal/Brønsted acid cooperative catalysis enabled facile synthesis of 8-hydroxyquinolines through one-pot reactions of ortho-aminophenol, aldehydes and alkynes
title_short Transition metal/Brønsted acid cooperative catalysis enabled facile synthesis of 8-hydroxyquinolines through one-pot reactions of ortho-aminophenol, aldehydes and alkynes
title_sort transition metal/brønsted acid cooperative catalysis enabled facile synthesis of 8-hydroxyquinolines through one-pot reactions of ortho-aminophenol, aldehydes and alkynes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086736/
https://www.ncbi.nlm.nih.gov/pubmed/35548801
http://dx.doi.org/10.1039/c8ra07212d
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