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Evaluation of a Multiethnic Polygenic Risk Score Model for Prostate Cancer
Polygenic risk scores (PRSs) of common genetic variants have shown promise in prostate cancer risk stratification, but their validity across populations has yet to be confirmed. We evaluated a multiethnic PRS model based on 269 germline genetic risk variants (261 were available for analysis) using a...
Autores principales: | Plym, Anna, Penney, Kathryn L, Kalia, Sarah, Kraft, Peter, Conti, David V, Haiman, Christopher, Mucci, Lorelei A, Kibel, Adam S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086757/ https://www.ncbi.nlm.nih.gov/pubmed/33792693 http://dx.doi.org/10.1093/jnci/djab058 |
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