ATM Germline-Mutated Gastroesophageal Junction Adenocarcinomas: Clinical Descriptors, Molecular Characteristics, and Potential Therapeutic Implications

BACKGROUND: Gastroesophageal junction (GEJ) adenocarcinoma is a rare cancer associated with poor prognosis. The genetic factors conferring predisposition to GEJ adenocarcinoma have yet to be identified. METHODS: We analyzed germline testing results from 23 381 cancer patients undergoing tumor-normal...

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Detalles Bibliográficos
Autores principales: El Jabbour, Tony, Misyura, Maksym, Cowzer, Darren, Zimmermann, Michal, Rimkunas, Victoria, Marra, Antonio, Derakhshan, Fatemeh, Selenica, Pier, Parilla, Megan, Setton, Jeremy S, Ceyhan-Birsoy, Ozge, Kemel, Yelena, Catchings, Amanda, Ranganathan, Megha, Ku, Geoffrey Y, Janjigian, Yelena Y, Zinda, Michael, Koehler, Maria, Stadler, Zsofia, Shia, Jinru, Reis-Filho, Jorge S, Mandelker, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086803/
https://www.ncbi.nlm.nih.gov/pubmed/35078243
http://dx.doi.org/10.1093/jnci/djac024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086803/
https://www.ncbi.nlm.nih.gov/pubmed/35078243
http://dx.doi.org/10.1093/jnci/djac024

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