An efficient strategy for a controllable droplet merging system for digital analysis

Droplet merging is an important part of droplet manipulation approaches. Droplet merging methods with expansions inside channels can merge droplets in pairs through simple structures. However, they have a low success rate of merging under unstable fluidic conditions since the one-to-one pairing stra...

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Detalles Bibliográficos
Autores principales: Qiao, Yi, Fu, Jiye, Yang, Fang, Duan, Mengqin, Huang, Mengting, Tu, Jing, Lu, Zuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086890/
https://www.ncbi.nlm.nih.gov/pubmed/35548645
http://dx.doi.org/10.1039/c8ra06022c
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author Qiao, Yi
Fu, Jiye
Yang, Fang
Duan, Mengqin
Huang, Mengting
Tu, Jing
Lu, Zuhong
author_facet Qiao, Yi
Fu, Jiye
Yang, Fang
Duan, Mengqin
Huang, Mengting
Tu, Jing
Lu, Zuhong
author_sort Qiao, Yi
collection PubMed
description Droplet merging is an important part of droplet manipulation approaches. Droplet merging methods with expansions inside channels can merge droplets in pairs through simple structures. However, they have a low success rate of merging under unstable fluidic conditions since the one-to-one pairing strategy is sensitive to fluctuation. This study presents a one-to-a-cluster pairing strategy to improve the success rate of merging under fluctuation. The one-to-a-cluster method was suitable for digital analysis and droplet MDA was performed in merged droplets successfully.
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spelling pubmed-90868902022-05-10 An efficient strategy for a controllable droplet merging system for digital analysis Qiao, Yi Fu, Jiye Yang, Fang Duan, Mengqin Huang, Mengting Tu, Jing Lu, Zuhong RSC Adv Chemistry Droplet merging is an important part of droplet manipulation approaches. Droplet merging methods with expansions inside channels can merge droplets in pairs through simple structures. However, they have a low success rate of merging under unstable fluidic conditions since the one-to-one pairing strategy is sensitive to fluctuation. This study presents a one-to-a-cluster pairing strategy to improve the success rate of merging under fluctuation. The one-to-a-cluster method was suitable for digital analysis and droplet MDA was performed in merged droplets successfully. The Royal Society of Chemistry 2018-10-05 /pmc/articles/PMC9086890/ /pubmed/35548645 http://dx.doi.org/10.1039/c8ra06022c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Qiao, Yi
Fu, Jiye
Yang, Fang
Duan, Mengqin
Huang, Mengting
Tu, Jing
Lu, Zuhong
An efficient strategy for a controllable droplet merging system for digital analysis
title An efficient strategy for a controllable droplet merging system for digital analysis
title_full An efficient strategy for a controllable droplet merging system for digital analysis
title_fullStr An efficient strategy for a controllable droplet merging system for digital analysis
title_full_unstemmed An efficient strategy for a controllable droplet merging system for digital analysis
title_short An efficient strategy for a controllable droplet merging system for digital analysis
title_sort efficient strategy for a controllable droplet merging system for digital analysis
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086890/
https://www.ncbi.nlm.nih.gov/pubmed/35548645
http://dx.doi.org/10.1039/c8ra06022c
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