Risk Factors and Biomarkers for Immune-Related Adverse Events: A Practical Guide to Identifying High-Risk Patients and Rechallenging Immune Checkpoint Inhibitors

Immune-related adverse events (irAEs) are a range of complications associated with the use of immune-checkpoint inhibitors (ICIs). Two major classes of ICIs widely used are Cytotoxic T-Lymphocyte Antigen 4 (CTLA4) and Programmed Cell death-1 (PD-1)/Programmed death-ligand 1 (PD-L1) inhibitors. High-...

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Detalles Bibliográficos
Autores principales: Chennamadhavuni, Adithya, Abushahin, Laith, Jin, Ning, Presley, Carolyn J., Manne, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086893/
https://www.ncbi.nlm.nih.gov/pubmed/35558065
http://dx.doi.org/10.3389/fimmu.2022.779691

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