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A Polygenic Score for Type 2 Diabetes Improves Risk Stratification Beyond Current Clinical Screening Factors in an Ancestrally Diverse Sample

A substantial proportion of the adult United States population with type 2 diabetes (T2D) are undiagnosed, calling into question the comprehensiveness of current screening practices, which primarily rely on age, family history, and body mass index (BMI). We hypothesized that a polygenic score (PGS)...

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Detalles Bibliográficos
Autores principales:	Ashenhurst, James R., Sazonova, Olga V., Svrchek, Olivia, Detweiler, Stacey, Kita, Ryosuke, Babalola, Liz, McIntyre, Matthew, Aslibekyan, Stella, Fontanillas, Pierre, Shringarpure, Suyash, Pollard, Jeffrey D., Koelsch, Bertram L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086969/ https://www.ncbi.nlm.nih.gov/pubmed/35559025 http://dx.doi.org/10.3389/fgene.2022.871260

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