Cargando…

Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide‐Based Hybrid Compounds against SARS‐CoV‐2 and Cancer

The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) cause life‐threatening diseases in millions of people worldwide, in particular, in patients with cancer, and there is an urgent need for antiviral agents against this infection. While in vitro activities of artemisinins a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Herrmann, Lars, Yaremenko, Ivan A., Çapcı, Aysun, Struwe, Julia, Tailor, Dhanir, Dheeraj, Arpit, Hodek, Jan, Belyakova, Yulia Yu., Radulov, Peter S., Weber, Jan, Malhotra, Sanjay V., Terent'ev, Alexander O., Ackermann, Lutz, Tsogoeva, Svetlana B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086992/ https://www.ncbi.nlm.nih.gov/pubmed/35187791 http://dx.doi.org/10.1002/cmdc.202200005

Ejemplares similares

Lewis Acids and Heteropoly Acids in the Synthesis of Organic Peroxides
por: Yaremenko, Ivan A., et al.
Publicado: (2022)

Synthetic Strategies for Peroxide Ring Construction in Artemisinin
por: Vil’, Vera A., et al.
Publicado: (2017)

Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees
por: Yaremenko, Ivan A., et al.
Publicado: (2020)

(Iso)Quinoline–Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses
por: Çapcı, Aysun, et al.
Publicado: (2020)

Bridged 1,2,4-Trioxolanes: SnCl(4)—Catalyzed Synthesis and an In Vitro Study against S. mansoni
por: Radulov, Peter S., et al.
Publicado: (2023)

Rearrangements of organic peroxides and related processes
por: Yaremenko, Ivan A, et al.
Publicado: (2016)

Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions
por: Vil’, Vera A., et al.
Publicado: (2017)

Chemical hybridization of sulfasalazine and dihydroartemisinin promotes brain tumor cell death
por: Ackermann, Annemarie, et al.
Publicado: (2021)

[Image: see text] Synthesis of cyclic aza-peroxides (microreview)
por: Belyakova, Yulia Yu., et al.
Publicado: (2021)

Studies of Potency and Efficacy of an Optimized Artemisinin-Quinoline Hybrid against Multiple Stages of the Plasmodium Life Cycle
por: Quadros, Helenita C., et al.
Publicado: (2021)

Autofluorescent antimalarials by hybridization of artemisinin and coumarin: in vitro/in vivo studies and live-cell imaging
por: Herrmann, Lars, et al.
Publicado: (2023)

Synthesis of five- and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products
por: Terent'ev, Alexander O, et al.
Publicado: (2014)

Stereoelectronic source of the anomalous stability of bis-peroxides
por: Gomes, Gabriel dos Passos, et al.
Publicado: (2015)

Cytotoxic profiling of artesunic and betulinic acids and their synthetic hybrid compound on neurons and gliomas
por: Ackermann, Annemarie, et al.
Publicado: (2017)

[Image: see text] Application of BF(3)·Et(2)O in the synthesis of cyclic organic peroxides (microreview)
por: Radulov, Peter S., et al.
Publicado: (2020)

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria
por: Çapcı, Aysun, et al.
Publicado: (2019)

Climate Change as a Factor in the Development of Companies: Corporate Strategies and Guidelines for State Industrial Policy
por: Terent’ev, N. E.
Publicado: (2021)

The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity Based on a Mitochondrial Targeting Mechanism
por: Wild, Markus, et al.
Publicado: (2020)

Guanylate-Binding Protein 1: An Emerging Target in Inflammation and Cancer
por: Honkala, Alexander T., et al.
Publicado: (2020)

Synthesis of Tamoxifen‐Artemisinin and Estrogen‐Artemisinin Hybrids Highly Potent Against Breast and Prostate Cancer
por: Fröhlich, Tony, et al.
Publicado: (2020)

Electrochemically Induced Synthesis of Imidazoles from Vinyl Azides and Benzyl Amines
por: Vil’, Vera A., et al.
Publicado: (2022)

Iminoxyl radicals vs. tert-butylperoxyl radical in competitive oxidative C–O coupling with β-dicarbonyl compounds. Oxime ether formation prevails over Kharasch peroxidation
por: Krylov, I. B., et al.
Publicado: (2018)

Cross-dehydrogenative coupling for the intermolecular C–O bond formation
por: Krylov, Igor B, et al.
Publicado: (2015)

NO-Donor Iron Nitrosyl Complex with N-Ethylthiourea Ligand Exhibits Selective Toxicity to Glioma A172 Cells
por: Sanina, Nataliya, et al.
Publicado: (2017)

Oxime radicals: generation, properties and application in organic synthesis
por: Krylov, Igor B, et al.
Publicado: (2020)

Spectral data of refractive index and extinction coefficient for thin films of titanium group metals used for fabrication of optical microstructures
por: Belousov, Dmitrij A., et al.
Publicado: (2019)

Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds
por: Gruber, Lisa, et al.
Publicado: (2018)

Redox-active molecules as organocatalysts for selective oxidative transformations – an unperceived organocatalysis field
por: Lopat’eva, Elena R, et al.
Publicado: (2022)

Guanylate-binding protein 1 modulates proteasomal machinery in ovarian cancer
por: Tailor, Dhanir, et al.
Publicado: (2023)

A H(2)O(2)/HBr system – several directions but one choice: oxidation–bromination of secondary alcohols into mono- or dibromo ketones
por: Nikishin, Gennady I., et al.
Publicado: (2018)

Heterogeneous Photocatalysis as a Potent Tool for Organic Synthesis: Cross-Dehydrogenative C–C Coupling of N-Heterocycles with Ethers Employing TiO(2)/N-Hydroxyphthalimide System under Visible Light
por: Lopat’eva, Elena R., et al.
Publicado: (2023)

Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells
por: Fröhlich, Tony, et al.
Publicado: (2017)

Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer
por: Tailor, Dhanir, et al.
Publicado: (2020)

Reengineering Ponatinib to Minimize Cardiovascular Toxicity
por: Hnatiuk, Anna P., et al.
Publicado: (2022)

Widespread Availability of Artemisinin Monotherapy in the United States
por: Rakita, Robert M., et al.
Publicado: (2011)

Synthesis of unstrained Criegee intermediates: inverse α-effect and other protective stereoelectronic forces can stop Baeyer–Villiger rearrangement of γ-hydroperoxy-γ-peroxylactones
por: Vil', Vera A., et al.
Publicado: (2020)

Anti‐SARS‐CoV‐2 Inhibitory Profile of New Quinoline Compounds in Cell Culture‐Based Infection Models
por: Herrmann, Lars, et al.
Publicado: (2021)

Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells
por: Ndreshkjana, Benardina, et al.
Publicado: (2019)

Impact of an Immune Modulator Mycobacterium-w on Adaptive Natural Killer Cells and Protection Against COVID-19
por: Jaiswal, Sarita Rani, et al.
Publicado: (2022)

Hypervalent iodine compounds for anti-Markovnikov-type iodo-oxyimidation of vinylarenes
por: Krylov, Igor B, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_052vo039e08ojcr55c3spdcfdb