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The Association of Triglyceride Glucose index for Coronary Artery Disease in Postmenopausal Women

This study aimed to explore the association between the triglyceride glucose (TyG) index and coronary artery disease (CAD) in postmenopausal women. This study enrolled 869 postmenopausal women and classified them into two groups: CAD group (n  =  538) and control group (n  =  331). The TyG index was...

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Autores principales: Liu, Jingyi, Bu, Haiwei, Ding, Zhenjiang, Zhang, Ying, Chen, Yongjie, Gao, Yuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087225/
https://www.ncbi.nlm.nih.gov/pubmed/35469448
http://dx.doi.org/10.1177/10760296221094030
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author Liu, Jingyi
Bu, Haiwei
Ding, Zhenjiang
Zhang, Ying
Chen, Yongjie
Gao, Yuxia
author_facet Liu, Jingyi
Bu, Haiwei
Ding, Zhenjiang
Zhang, Ying
Chen, Yongjie
Gao, Yuxia
author_sort Liu, Jingyi
collection PubMed
description This study aimed to explore the association between the triglyceride glucose (TyG) index and coronary artery disease (CAD) in postmenopausal women. This study enrolled 869 postmenopausal women and classified them into two groups: CAD group (n  =  538) and control group (n  =  331). The TyG index was significantly higher in patients with CAD than in controls (P < 0.05).Receiver operator characteristic curves showed that the TyG index was more discriminative for CAD than for control group, and after adjusting for the traditional clinical prognostic factors, including age (>60 years), diabetes, ischemic stroke, systolic blood pressure (≥140), and ejection fraction (<50%), we found that the TyG index could be an independent risk factor for CAD (P < 0.05). The risk of increased TyG index was greater in the <50 years subgroup than in the >50 years subgroup (P < 0.05). The TyG index may be a valuable clinical predictor of CAD risk in postmenopausal women.
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spelling pubmed-90872252022-05-11 The Association of Triglyceride Glucose index for Coronary Artery Disease in Postmenopausal Women Liu, Jingyi Bu, Haiwei Ding, Zhenjiang Zhang, Ying Chen, Yongjie Gao, Yuxia Clin Appl Thromb Hemost Original Manuscript This study aimed to explore the association between the triglyceride glucose (TyG) index and coronary artery disease (CAD) in postmenopausal women. This study enrolled 869 postmenopausal women and classified them into two groups: CAD group (n  =  538) and control group (n  =  331). The TyG index was significantly higher in patients with CAD than in controls (P < 0.05).Receiver operator characteristic curves showed that the TyG index was more discriminative for CAD than for control group, and after adjusting for the traditional clinical prognostic factors, including age (>60 years), diabetes, ischemic stroke, systolic blood pressure (≥140), and ejection fraction (<50%), we found that the TyG index could be an independent risk factor for CAD (P < 0.05). The risk of increased TyG index was greater in the <50 years subgroup than in the >50 years subgroup (P < 0.05). The TyG index may be a valuable clinical predictor of CAD risk in postmenopausal women. SAGE Publications 2022-04-25 /pmc/articles/PMC9087225/ /pubmed/35469448 http://dx.doi.org/10.1177/10760296221094030 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Manuscript
Liu, Jingyi
Bu, Haiwei
Ding, Zhenjiang
Zhang, Ying
Chen, Yongjie
Gao, Yuxia
The Association of Triglyceride Glucose index for Coronary Artery Disease in Postmenopausal Women
title The Association of Triglyceride Glucose index for Coronary Artery Disease in Postmenopausal Women
title_full The Association of Triglyceride Glucose index for Coronary Artery Disease in Postmenopausal Women
title_fullStr The Association of Triglyceride Glucose index for Coronary Artery Disease in Postmenopausal Women
title_full_unstemmed The Association of Triglyceride Glucose index for Coronary Artery Disease in Postmenopausal Women
title_short The Association of Triglyceride Glucose index for Coronary Artery Disease in Postmenopausal Women
title_sort association of triglyceride glucose index for coronary artery disease in postmenopausal women
topic Original Manuscript
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087225/
https://www.ncbi.nlm.nih.gov/pubmed/35469448
http://dx.doi.org/10.1177/10760296221094030
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