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A novel anti-lung cancer agent inhibits proliferation and epithelial–mesenchymal transition

OBJECTIVE: To synthesize a novel chalcone-1,3,4-thiadiazole hybrid and investigate its anticancer effects against NCI-H460 cells. METHODS: (E)-3-(4-bromophenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one, 1,3-dibromopropane and 1,3,4-thiadiazole-2-thiol were used as chemical materials to synthesize compound...

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Detalles Bibliográficos
Autores principales:	Zhao, Wen, Xu, Ye, Guo, Qingkui, Qian, Wenliang, Zhu, Chen, Zheng, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Pre-Clinical Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087257/ https://www.ncbi.nlm.nih.gov/pubmed/35477254 http://dx.doi.org/10.1177/03000605211066300

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