Cargando…
Differential diagnostic value of the ResNet50, random forest, and DS ensemble models for papillary thyroid carcinoma and other thyroid nodules
Objective To explore the differential diagnostic efficiency of the residual network (ResNet)50, random forest (RF), and DS ensemble models for papillary thyroid carcinoma (PTC) and other pathological types of thyroid nodules. Methods This study retrospectively analyzed 559 patients with thyroid nodu...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087260/ https://www.ncbi.nlm.nih.gov/pubmed/35469474 http://dx.doi.org/10.1177/03000605221094276 |
_version_ | 1784704165074698240 |
---|---|
author | Deng, Chengwen Han, Dongyan Feng, Ming Lv, Zhongwei Li, Dan |
author_facet | Deng, Chengwen Han, Dongyan Feng, Ming Lv, Zhongwei Li, Dan |
author_sort | Deng, Chengwen |
collection | PubMed |
description | Objective To explore the differential diagnostic efficiency of the residual network (ResNet)50, random forest (RF), and DS ensemble models for papillary thyroid carcinoma (PTC) and other pathological types of thyroid nodules. Methods This study retrospectively analyzed 559 patients with thyroid nodules and collected thyroid pathological images and auxiliary examination results (laboratory and ultrasound results) to construct datasets. The pathological image dataset was used to train a ResNet50 model, the text dataset was used to train a random forest (RF) model, and a DS ensemble model was constructed from the results of the two models. The differential diagnostic values of the three models for PTC and other types of thyroid nodules were then compared. Results The DS ensemble model had the highest sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve (85.87%, 97.18%, 93.77%, and 0.982, respectively). Conclusions Compared with Resnet50 and the RF models trained only on imaging data or text information, respectively, the DS ensemble model showed better diagnostic value for PTC. |
format | Online Article Text |
id | pubmed-9087260 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-90872602022-05-11 Differential diagnostic value of the ResNet50, random forest, and DS ensemble models for papillary thyroid carcinoma and other thyroid nodules Deng, Chengwen Han, Dongyan Feng, Ming Lv, Zhongwei Li, Dan J Int Med Res Retrospective Clinical Research Report Objective To explore the differential diagnostic efficiency of the residual network (ResNet)50, random forest (RF), and DS ensemble models for papillary thyroid carcinoma (PTC) and other pathological types of thyroid nodules. Methods This study retrospectively analyzed 559 patients with thyroid nodules and collected thyroid pathological images and auxiliary examination results (laboratory and ultrasound results) to construct datasets. The pathological image dataset was used to train a ResNet50 model, the text dataset was used to train a random forest (RF) model, and a DS ensemble model was constructed from the results of the two models. The differential diagnostic values of the three models for PTC and other types of thyroid nodules were then compared. Results The DS ensemble model had the highest sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve (85.87%, 97.18%, 93.77%, and 0.982, respectively). Conclusions Compared with Resnet50 and the RF models trained only on imaging data or text information, respectively, the DS ensemble model showed better diagnostic value for PTC. SAGE Publications 2022-04-25 /pmc/articles/PMC9087260/ /pubmed/35469474 http://dx.doi.org/10.1177/03000605221094276 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Retrospective Clinical Research Report Deng, Chengwen Han, Dongyan Feng, Ming Lv, Zhongwei Li, Dan Differential diagnostic value of the ResNet50, random forest, and DS ensemble models for papillary thyroid carcinoma and other thyroid nodules |
title | Differential diagnostic value of the ResNet50, random forest, and DS
ensemble models for papillary thyroid carcinoma and other thyroid
nodules |
title_full | Differential diagnostic value of the ResNet50, random forest, and DS
ensemble models for papillary thyroid carcinoma and other thyroid
nodules |
title_fullStr | Differential diagnostic value of the ResNet50, random forest, and DS
ensemble models for papillary thyroid carcinoma and other thyroid
nodules |
title_full_unstemmed | Differential diagnostic value of the ResNet50, random forest, and DS
ensemble models for papillary thyroid carcinoma and other thyroid
nodules |
title_short | Differential diagnostic value of the ResNet50, random forest, and DS
ensemble models for papillary thyroid carcinoma and other thyroid
nodules |
title_sort | differential diagnostic value of the resnet50, random forest, and ds
ensemble models for papillary thyroid carcinoma and other thyroid
nodules |
topic | Retrospective Clinical Research Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087260/ https://www.ncbi.nlm.nih.gov/pubmed/35469474 http://dx.doi.org/10.1177/03000605221094276 |
work_keys_str_mv | AT dengchengwen differentialdiagnosticvalueoftheresnet50randomforestanddsensemblemodelsforpapillarythyroidcarcinomaandotherthyroidnodules AT handongyan differentialdiagnosticvalueoftheresnet50randomforestanddsensemblemodelsforpapillarythyroidcarcinomaandotherthyroidnodules AT fengming differentialdiagnosticvalueoftheresnet50randomforestanddsensemblemodelsforpapillarythyroidcarcinomaandotherthyroidnodules AT lvzhongwei differentialdiagnosticvalueoftheresnet50randomforestanddsensemblemodelsforpapillarythyroidcarcinomaandotherthyroidnodules AT lidan differentialdiagnosticvalueoftheresnet50randomforestanddsensemblemodelsforpapillarythyroidcarcinomaandotherthyroidnodules |