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NHC–BIAN–Cu(I)-Catalyzed Friedländer-Type Annulation of 2-Amino-3-(per)fluoroacetylpyridines with Alkynes on Water

[Image: see text] The direct catalytic alkynylation/dehydrative cyclization of 2-amino-3-trifluoroacetyl-pyridines on water was developed for the efficient synthesis of a broad range of fluorinated 1,8-naphthyridines from terminal alkynes. A novel N-heterocyclic carbene (NHC) ligand system that comb...

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Detalles Bibliográficos
Autores principales:	Dolna, Magdalena, Nowacki, Michał, Danylyuk, Oksana, Brotons-Rufes, Artur, Poater, Albert, Michalak, Michał
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087358/ https://www.ncbi.nlm.nih.gov/pubmed/35394784 http://dx.doi.org/10.1021/acs.joc.2c00380

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