FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma

BACKGROUND: Melanoma is a type of malignant tumor with high aggressiveness and poor prognosis. At present, metastasis of melanoma is still an important cause of death in melanoma patients. However, the potential functions and molecular mechanisms of most circular RNAs (circRNAs) in melanoma metastas...

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Detalles Bibliográficos
Autores principales: Shang, Qingfeng, Du, Haizhen, Wu, Xiaowen, Guo, Qian, Zhang, Fenghao, Gong, Ziqi, Jiao, Tao, Guo, Jun, Kong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087950/
https://www.ncbi.nlm.nih.gov/pubmed/35534866
http://dx.doi.org/10.1186/s13046-022-02357-7

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