N(6)-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma

BACKGROUND: Sunitinib resistance can be classified into primary and secondary resistance. While accumulating research has indicated several underlying factors contributing to sunitinib resistance, the precise mechanisms in renal cell carcinoma are still unclear. METHODS: RNA sequencing and m6A seque...

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Detalles Bibliográficos
Autores principales: Chen, Yuanlei, Lu, Zeyi, Qi, Chao, Yu, Chenhao, Li, Yang, Huan, Wang, Wang, Ruyue, Luo, Wenqin, Shen, Danyang, Ding, Lifeng, Ren, Liangliang, Xie, Haiyun, Xue, Dingwei, Wang, Mingchao, Ni, Kangxin, Xia, Liqun, Qian, Jun, Li, Gonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087993/
https://www.ncbi.nlm.nih.gov/pubmed/35538475
http://dx.doi.org/10.1186/s12943-022-01549-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087993/
https://www.ncbi.nlm.nih.gov/pubmed/35538475
http://dx.doi.org/10.1186/s12943-022-01549-1

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