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N(6)-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma
BACKGROUND: Sunitinib resistance can be classified into primary and secondary resistance. While accumulating research has indicated several underlying factors contributing to sunitinib resistance, the precise mechanisms in renal cell carcinoma are still unclear. METHODS: RNA sequencing and m6A seque...
Autores principales: | Chen, Yuanlei, Lu, Zeyi, Qi, Chao, Yu, Chenhao, Li, Yang, Huan, Wang, Wang, Ruyue, Luo, Wenqin, Shen, Danyang, Ding, Lifeng, Ren, Liangliang, Xie, Haiyun, Xue, Dingwei, Wang, Mingchao, Ni, Kangxin, Xia, Liqun, Qian, Jun, Li, Gonghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087993/ https://www.ncbi.nlm.nih.gov/pubmed/35538475 http://dx.doi.org/10.1186/s12943-022-01549-1 |
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