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Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)

BACKGROUND: Copper oxide (CuO) nanoparticles (NPs) are known to trigger cytotoxicity in a variety of cell models, but the mechanism of cell death remains unknown. Here we addressed the mechanism of cytotoxicity in macrophages exposed to CuO NPs versus copper chloride (CuCl(2)). METHODS: The mouse ma...

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Detalles Bibliográficos
Autores principales:	Gupta, Govind, Cappellini, Francesca, Farcal, Lucian, Gornati, Rosalba, Bernardini, Giovanni, Fadeel, Bengt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088059/ https://www.ncbi.nlm.nih.gov/pubmed/35538581 http://dx.doi.org/10.1186/s12989-022-00467-w

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