Durable immunogenicity, adaptation to emerging variants, and low-dose efficacy of an AAV-based COVID-19 vaccine platform in macaques

The COVID-19 pandemic continues to have devastating consequences on health and economy, even after the approval of safe and effective vaccines. Waning immunity, the emergence of variants of concern, breakthrough infections, and lack of global vaccine access and acceptance perpetuate the epidemic. He...

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Detalles Bibliográficos
Autores principales: Zabaleta, Nerea, Bhatt, Urja, Hérate, Cécile, Maisonnasse, Pauline, Sanmiguel, Julio, Diop, Cheikh, Castore, Sofia, Estelien, Reynette, Li, Dan, Dereuddre-Bosquet, Nathalie, Cavarelli, Mariangela, Gallouët, Anne-Sophie, Pascal, Quentin, Naninck, Thibaut, Kahlaoui, Nidhal, Lemaitre, Julien, Relouzat, Francis, Ronzitti, Giuseppe, Thibaut, Hendrik Jan, Montomoli, Emanuele, Wilson, James M., Le Grand, Roger, Vandenberghe, Luk H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088091/
https://www.ncbi.nlm.nih.gov/pubmed/35546782
http://dx.doi.org/10.1016/j.ymthe.2022.05.007

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