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Patient-derived xenograft (PDX) models, applications and challenges in cancer research
The establishing of the first cancer models created a new perspective on the identification and evaluation of new anti-cancer therapies in preclinical studies. Patient-derived xenograft models are created by tumor tissue engraftment. These models accurately represent the biology and heterogeneity of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088152/ https://www.ncbi.nlm.nih.gov/pubmed/35538576 http://dx.doi.org/10.1186/s12967-022-03405-8 |