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Easy-to-Implement Hydrogen Isotope Exchange for the Labeling of N-Heterocycles, Alkylkamines, Benzylic Scaffolds, and Pharmaceuticals
[Image: see text] Facilitating access to deuterated and tritiated complex molecules is of paramount importance due to the fundamental role of isotopically labeled compounds in drug discovery and development. Deuterated analogues of drugs are extensively used as internal standards for quantification...
Autores principales: | Levernier, Etienne, Tatoueix, Kevin, Garcia-Argote, Sébastien, Pfeifer, Viktor, Kiesling, Ralf, Gravel, Edmond, Feuillastre, Sophie, Pieters, Grégory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088292/ https://www.ncbi.nlm.nih.gov/pubmed/35557763 http://dx.doi.org/10.1021/jacsau.1c00503 |
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