The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate against Shigella

[Image: see text] Shigella, the causative agent of shigellosis, is among the main causes of diarrheal diseases with still a high morbidity in low-income countries. Relying on chemical synthesis, we implemented a multidisciplinary strategy to design SF2a-TT15, an original glycoconjugate vaccine candi...

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Detalles Bibliográficos
Autores principales: van der Put, Robert M. F., Smitsman, Carolien, de Haan, Alex, Hamzink, Martin, Timmermans, Hans, Uittenbogaard, Joost, Westdijk, Janny, Stork, Michiel, Ophorst, Olga, Thouron, Françoise, Guerreiro, Catherine, Sansonetti, Philippe J., Phalipon, Armelle, Mulard, Laurence A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088300/
https://www.ncbi.nlm.nih.gov/pubmed/35559427
http://dx.doi.org/10.1021/acscentsci.1c01479

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