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Merging Directed C–H Activations with High-Throughput Experimentation: Development of Iridium-Catalyzed C–H Aminations Applicable to Late-Stage Functionalization

[Image: see text] Herein, we report an iridium-catalyzed directed C–H amination methodology developed using a high-throughput experimentation (HTE)-based strategy, applicable for the needs of automated modern drug discovery. The informer library approach for investigating the accessible directing gr...

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Detalles Bibliográficos
Autores principales:	Weis, Erik, Johansson, Maria, Korsgren, Pernilla, Martín-Matute, Belén, Johansson, Magnus J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088304/ https://www.ncbi.nlm.nih.gov/pubmed/35557751 http://dx.doi.org/10.1021/jacsau.2c00039

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