Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature

A patient with advanced HIV/AIDS presented with a brain abscess. While brain biopsy culture and pathology were unrevealing, universal broad-range polymerase chain reaction (uPCR) demonstrated Mycobacterium avium complex (MAC). We review the clinicopathologic characteristics of MAC brain abscesses an...

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Detalles Bibliográficos
Autores principales: Lane-Donovan, Courtney, Bainbridge, Emma, Szumowski, John, Kerkhoff, Andrew D, Peluso, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Novel ID Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088507/
https://www.ncbi.nlm.nih.gov/pubmed/35559128
http://dx.doi.org/10.1093/ofid/ofab450
Descripción
Sumario:A patient with advanced HIV/AIDS presented with a brain abscess. While brain biopsy culture and pathology were unrevealing, universal broad-range polymerase chain reaction (uPCR) demonstrated Mycobacterium avium complex (MAC). We review the clinicopathologic characteristics of MAC brain abscesses and highlight the effectiveness of uPCR as a diagnostic tool in partially treated infections.

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